Looking for new treatments of Infantile Colic

Abstract

Infantile colic is a common disturbance occurring in the first three months of life. It is a benign condition and one of the main causes of pediatric consultation in the early part of life because of its great impact on family life. Some pediatricians are prone to undervalue this issue mainly because of the lack of evidence based medicine guidelines. Up to now, there is no consensus concerning management and treatment. Literature reports growing evidence about the effectiveness of dietary, pharmacological, complementary and behavioral therapies as options for the management of infantile colic. Dietary approach, usually based on the avoidance of cow’s milk proteins in breast-feeding mothers and bottle-fed infants, more recently has seen the rise of new special formulas, such as partially hydrolyzed proteins and low lactose added with prebiotics or probiotics: their efficacy needs to be further documented. Investigated pharmacological agents are Simethicone and Cimetropium Bromide: the first is able to reduce bloating while the second could reduce fussing crying, but it has been tested only for severe infantile colic. No other pain relieving agents have been proposed until now, but some clinical trials are ongoing for new drugs.There is limited evidence supporting the use of complementary and alternative treatments (herbal supplements, manipulative approach and acupuncture) or behavioral interventions.Recent studies have focused the role of microbiota in the pathogenesis of this disturb and so new treatments, such as probiotics, have been proposed, but only few strains have been tested.Further investigations are needed in order to provide evidence-based guidelines.

Child Care among Primiparous and Multiparous Women in a Birth Cohort Study

“…A study showed that most of the mothers knew of some type of alternative treatment such as bath with herbs, virgin tile and white rose, as well as sun exposure. They had perception about the effectiveness or not of the practices and some reported previous use or intention to do it after hospital discharge [27].…”

Current Issues of Diagnosis and Treatment of Functional Gastrointestinal Disorders in Children

“…Завершающая фаза функционального созревания кишечника начинается при рождении ребенка [11]. Исследования последних лет подтвердили, что регуля-цию развития кишечника осуществляют амниотическая жидкость, молозиво, грудное молоко, микробиота, цир-кулирующие в крови факторы роста, глюкокортикостеро-иды и другие эндогенные факторы [12].…”

İnfantil kolik tanı ve tedavisinde güncel yaklaşımlar

“…Aynı şekilde standart mama ile yeterli ağırlık artımı var ve inek sütü proteini alerjisi öykü ve semptomu yoksa hidrolize mamaya geçiş önerilmemektedir (40). Kolikli bebeklerde laktaz enzimli ya da liften zengin mamaların ve laktaz enziminin kullanımı ile ilgili yeterli veri olmadığı da çalışmalarda gösterilmiştir (38). Alternatif besinler içinde oral sükroz kullanımı bir dönem önerilmiş olup çalışma-larda bu konuda yeterli verinin olmaması nedeniyle artık rutinde önerilme-mektedir (46).…”