Lysosomal membrane stabilization and anti-inflammatory activity of Clerodendrum phlomidis L.f., a traditional medicinal plant

Documentation and quantitative analysis of the local knowledge on medicinal plants among traditional Siddha healers in Virudhunagar district of Tamil Nadu, India

“…The medicinal plants such as Clerodendrum phlomidis (Babu et al, 2011), Cardiospermum helicacabum (Sheeba and Asha, 2009) and Vitex negundo (Zheng et al, 2009) were having pharmacological support. The plants such as Abutilon indicum, Achyranthes aspera and Allium cepa were also reported for the treatment of hemorrhoids and lower gastrointestinal bleeding in our previous studies .…”

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“…Osteoclast activity can be directly induced by osteoblasts through the RANK/RANKL mechanism. [13] This adaptive immune response is initiated in part by CD4+ T helper (Th) cells, specifically Th17 cells. [5] Th17 cells are present in higher quantities at the site of bone destruction in joints and produce inflammatory cytokines associated with inflammation such as interleukin-17 (IL-17).…”

Phytochemical Screening and in Vitro Thrombolytic Activity of Clerodendrum Phlomidis Roots

“…The roots are used in the treatment of polyuria, cardiac diseases, oedema and diabetes. 7,8 The plant has been reported for anti-inflammatory 9,10 (leaf, aerial parts, root bark), antidiabetic 11 (stem), hepatoprotective 12 (whole plant), anti-arthritic 13 (leaves), antifungal 14 (leaves and stem), anti fertility 15 (root), immunomodulatory 16 (root) and anti-diarrhoeal 17 (leaves) activity. Several phytoconstituents have been reported in different parts of the plant particularly in roots ß-sitosterol, ceryl alcohol, clerodin, clerosterol and clerodendrin A were reported 18 .…”