Malignant lacrimal sac tumors

Abstract

Malignant epithelial lacrimal sac tumors are rare cancers with significant recurrence rates. Correct diagnosis and appropriate therapy require a multidisciplinary management approach. Treatment of these malignant epithelial tumors is first and foremost complete surgical removal with wide excision.

Adenoid cystic carcinoma of the lacrimal sac: case report

“…Although a late finding, hematogenous metastases are possible and (7) most commonly affect the lungs. Local lymph node involvement is rare (5)(6)(7) . From a histological standpoint, there are three types of ACC: cribriform, tubular, and solid.…”

“…The cribriform pattern is the most common and associated with the best prognosis, whereas the solid type is less frequent but has a poorer prognosis (3,7,8) . The most appropriate approach to the management of lacrimal sac tumors depends more on the tumoral size and the general condition of the patient rather than the histological type (5) . The classical treatment of malignant lacrimal sac tumors has been complete excision of the tumor and lacrimal drainage system, including the canaliculi and nasolacrimal duct, followed by radiotherapy and/or adjuvant chemotherapy (1,9) .…”

“…Lacrimal sac tumors should be considered in any patient with chronic epiphora or dacryocystitis who does not respond to standard treatments. Radiological studies with DCG, Computed Tomography (CT)-DCG, CT, and magnetic resonance imaging are essential in ruling the possibility of a lacrimal sac tumor (1,5) . In any case, pathological examinations are required for a definitive diagnosis of lacrimal sac tumor (4) .…”

“…As the most common signs of lacrimal sac tumors are epiphora or presence of a mass, the process can be incorrectly diagnosed as dacryostenosis or chronic dacryocystitis (DC) (1)(2)(3)(4) . Consequently, definitive diagnosis is delayed leading to worsened prognosis (5) . Adenoid cystic carcinoma (ACC) is an extremely rare form of malignant epithelial neoplasia of the lacrimal sac.…”

Mucoepidermoid carcinoma of lacrimal sac

“…Lacrimal sac is the closed upper end of the nasolacrimal duct and has a fibro-elastic wall lined internally by mucosa that is continuous with the conjunctiva through the lacrimal canaliculi and within the nasal mucosa through the nasolacrimal duct (1).primary lacrimal sac tumors are rare compared to other orbital tumors. Early treatment of these tumors is essential because they tend to be infiltrating tumors.…”