Metabolic changes during treatment with two different progestogens

Refn, H; Kjær, Andreas; Lebech, Anne‐Mette; Borggaard, Birgit; Schierup, L; Bremmelgaard, A.

doi:10.1016/0002-9378(90)90585-u

Cited by 29 publications

(1 citation statement)

References 12 publications

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“…Segesterone acetate is a novel progestin derived from progesterone. In contrast, many progestins used in combined hormonal contraception are derived from testosterone, and their androgenic activity may be responsible for changes in lipid profile, acne, and weight gain [18][19][20][21]. Segesterone acetate has 100-times higher progestational activity than progesterone as well as high anti-ovulatory potential for the prevention of pregnancy [18,19].…”

Section: Segesterone Acetatementioning

confidence: 99%

Long-Lasting, Patient-Controlled, Procedure-Free Contraception: A Review of Annovera with a Pharmacist Perspective

et al. 2020

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Annovera (segesterone acetate and ethinyl estradiol vaginal system) is a US Food and Drug Administration FDA-approved long-lasting, reversible contraceptive that is fully administered by the user and does not require a procedure for insertion or removal. The vaginal system is in the shape of a ring and contains low doses of a novel progestin, egesterone acetate, and ethinyl estradiol. It is made of silicone and is fully pliable and flexible. The vaginal system is reusable for 13 cycles, using a 21 days in/7 days out regimen, providing women with the ability to control their fertility. Particularly now during the COVID-19 pandemic when access to contraception has been further reduced, patients may benefit from a method that is both long-lasting and patient-controlled.

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