Mid-IR fibre optics spectroscopy in the 3300–600cm−1 range

Artyushenko, Viacheslav; Bocharnikov, Alexey; Colquhoun, Gary; Leach, C.; Lobachev, V. A.; Sakharova, Tatiana; Savitsky, D.

doi:10.1016/j.vibspec.2008.02.014

Cited by 31 publications

(13 citation statements)

References 5 publications

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“…According to the previous study (Artyushenko et al, 2008), the sensitivity of bent fiber-optic ATR sensor could be expressed by the ratio of effective evanescent absorption coefficient and bulk absorption coefficient of fluid surrounding the sensor. The numerous excellent properties of polycrystalline infrared (PIR) fibers (A.R.T.…”

Section: U-shaped Fiber-optic Atr Sensormentioning

confidence: 99%

“…The bent structure was constructive to increase the sensing optical length of the fiber-optic sensor in a limited space for implantable glucose measurement (Raichlin and Katzir, 2008). Compared with those of the conventional straight fiber-optic ATR sensor, each penetration depth and the total number of reflections were both increased after the fiber was bent (Artyushenko et al, 2008). Thus, the sensitivity and measurement resolution were improved.…”

Section: Introductionmentioning

confidence: 99%

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U-shaped fiber-optic ATR sensor enhanced by silver nanoparticles for continuous glucose monitoring

Shan-xin

Sun

et al. 2015

Biosensors and Bioelectronics

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Section: U-shaped Fiber-optic Atr Sensormentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

U-shaped fiber-optic ATR sensor enhanced by silver nanoparticles for continuous glucose monitoring

Shan-xin

Sun

et al. 2015

Biosensors and Bioelectronics

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“…Notable in this field are the works of Artyushenko et al, showing different mid-IR fiber-optic spectroscopic techniques which can be used for the analysis of samples in contact with such a mid-IR fiber. 28,29 These authors showed that such techniques may be used for medical diagnosis of cancerous tumors and other pathologies, which were at some distance from the FTIR spectrometer. 30,31 We too, developed a fiber-optic system, called fiber-optic evanescent wave spectroscopy (FEWS) system, that operates in the mid-IR in the spectral range of 3-30 µm.…”

Section: Introductionmentioning

confidence: 99%

Technical Note: Noninvasive mid‐IR fiber‐optic evanescent wave spectroscopy (FEWS) for early detection of skin cancers

Basov¹,

Dankner

Weinstein³

et al. 2020

Medical Physics

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Purpose Melanoma is the most lethal of the three primary skin cancers, including also basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), which are less lethal. The accepted diagnosis process involves manually observing a suspicious lesion through a Dermascope (i.e., a magnifying glass), followed by a biopsy. This process relies on the skill and the experience of a dermatologist. However, to the best of our knowledge, there is no accepted automatic, noninvasive, and rapid method for the early detection of the three types of skin cancer, distinguishing between them and noncancerous lesions, and identifying each of them. It is our aim to develop such a system. Methods We developed a fiber‐optic evanescent wave spectroscopy (FEWS) system based on middle infrared (mid‐IR) transmitting AgClBr fibers and a Fourier‐transform infrared spectrometer (FTIR). We used the system to perform mid‐IR spectral measurements on suspicious lesions in 90 patients, before biopsy, in situ, and in real time. The lesions were then biopsied and sent for pathology. The spectra were analyzed and the differences between pathological and healthy tissues were found and correlated. Results Five of the lesions measured were identified as melanomas, seven as BCC, and three as SCC. Using mathematical analyses of the spectra of these lesions we were able to tell that all were skin cancers and we found specific and easily identifiable differences between them. Conclusions This FEWS method lends itself to rapid, automatic and noninvasive early detection and characterization of skin cancers. It will be easily implemented in community clinics and has the potential to greatly simplify the diagnosis process.

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“…Common silica-glass fibers cannot transmit mid-infrared light with wavelengths longer than 2 µm because of absorption in the silica-glass material [1], so many types of infrared optical fibers have been developed, such as chalcogenide-glass fibers [2,3], metal-halide polycrystalline fibers [4,5], and hollow-core optical fibers [6,7]. Hollow-core optical fibers that confine light in an air core have some advantages over solid-core fibers for high-power laser delivery.…”

Section: Introductionmentioning

confidence: 99%

Fabrication of Shatter-Proof Metal Hollow-Core Optical Fibers for Endoscopic Mid-Infrared Laser Applications

Iwai

Takaku

Miyagi

et al. 2018

Fibers

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A method for fabricating robust and thin hollow-core optical fibers that carry mid-infrared light is proposed for use in endoscopic laser applications. The fiber is made of stainless steel tubing, eliminating the risk of scattering small glass fragments inside the body if the fiber breaks. To reduce the inner surface roughness of the tubing, a polymer base layer is formed prior to depositing silver and optical-polymer layers that confine light inside the hollow core. The surface roughness is greatly decreased by re-coating thin polymer base layers. Because of this smooth base layer surface, a uniform optical-polymer film can be formed around the core. As a result, clear interference peaks are observed in both the visible and mid-infrared regions. Transmission losses were also low for the carbon dioxide laser used for medical treatments as well as the visible laser diode used for an aiming beam. Measurements of bending losses for these lasers demonstrate the feasibility of the designed fiber for endoscopic applications.

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Mid-IR fibre optics spectroscopy in the 3300–600cm−1 range

Cited by 31 publications

References 5 publications

U-shaped fiber-optic ATR sensor enhanced by silver nanoparticles for continuous glucose monitoring

U-shaped fiber-optic ATR sensor enhanced by silver nanoparticles for continuous glucose monitoring

Technical Note: Noninvasive mid‐IR fiber‐optic evanescent wave spectroscopy (FEWS) for early detection of skin cancers

Fabrication of Shatter-Proof Metal Hollow-Core Optical Fibers for Endoscopic Mid-Infrared Laser Applications

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