Cognitive radio (CR) is a feasible intelligent technology and can be used as an effective solution to spectrum scarcity and underutilization. As the key function of CR, cooperative spectrum sensing (CSS) is able to effectively prevent the harmful interference with primary users (PUs) and identify the available spectrum resources by exploiting the spatial diversity of multiple secondary users (SUs). However, the open nature of the cognitive radio networks (CRNs) framework makes CSS face many security threats, such as, the malicious user (MU) launches Byzantine attack to undermine CRNs. For this aim, we make an in-depth analysis of the motive and purpose from the MU's perspective in the interweave CR system, aiming to provide the future guideline for defense strategies. First, we formulate a dynamic Byzantine attack model by analyzing Byzantine behaviors in the process of CSS. On the basis of this, we further make an investigation on the condition of making the fusion center (FC) blind when the fusion rule is unknown for the MU. Moreover, the throughput and interference to the primary network are taken into consideration to evaluate the impact of Byzantine attack on the interweave CR system, and then analyze the optimal strategy of Byzantine attack when the fusion rule is known. Finally, theoretical proofs and simulation results verify the correctness and effectiveness of analyses about the impact of Byzantine attack strategy on the throughput and interference.