The traditional bar code scanning in supermarkets is inefficient, which has been unable to meet the further development of a supermarket. To meet the needs of quick shopping in supermarkets, binary search algorithm has been proposed to prevent from anti-collision, which makes it faster to scan and identify the goods. On this basis, the goods which have not been checked out will be scanned again to obtain security. Besides, it plays an important role in the supermarket shopping system to achieve the functions of self-purchase and membership scheme. For the RFID supermarket shopping system, the test of the checkout efficiency, product recognition rate, and security were done. The result showed that the binary search algorithm had good accuracy in the RFID supermarket shopping system. The result also proved the rationality of the RFID supermarket shopping system, which can meet the daily needs of supermarkets. The method was applying the emerging technology into the traditional supermarket shopping system, which improved the profitability and management level of supermarkets.