Molecular Epidemiology and Clinical Manifestations of Viral Gastroenteritis in Hospitalized Pediatric Patients in Northern Taiwan

Chen, Shih Yen; Chang, Yu Chung; Lee, Yun Shien; Chao, Hsun Chin; Tsao, Kuo Chien; Lin, Tzou Yien; Ko, T. Y.; Tsai, Chia-Lung; Chiu, Cheng Hsun

doi:10.1128/jcm.01519-06

Cited by 72 publications

(60 citation statements)

References 15 publications

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“…These clinical manifestations are more severe than those of other causes of viral gastroenteritis (27). In our study, vomiting was associated with rotavirus positivity (Table 4), which aligns with the findings of other studies (20,28).…”

Section: Discussionsupporting

confidence: 81%

Identification of Rotavirus Strains Causing Diarrhoea in Children under Five Years of Age in Yogyakarta, Indonesian

Nirwati

Hakim

Aminah³

et al. 2017

MJMS

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Background: Rotavirus is an important cause of severe diarrhoea in children. The aims of this study were to identify the rotavirus strains that cause diarrhoea in children in Yogyakarta and to determine the association between rotavirus positivity and its clinical manifestations.Methods: Clinical data and stool samples were collected from children hospitalised at Kodya Yogyakarta Hospital, Indonesia. Rotavirus was detected in stool samples using an enzyme immunoassay (EIA), which was followed by genotyping using reverse transcriptase polymerase chain reaction (RT-PCR). Electropherotyping was performed for the rotavirus-positive samples.Results: In total, 104 cases were included in the study, 57 (54.8%) of which were rotavirus-positive. Based on a multiple logistic regression analysis, age group, vomiting and stool mucous were associated with rotavirus positivity. Most of the 56 samples subjected to genotyping were classified as G1 (80.36%) and P[8] (69.64%) genotypes. The genotype combination G1P[8] was identified as the most prevalent strain (66.07%). Of the 19 samples subjected to electropherotyping, 17 G1 isolates and 1 G3 isolate had long patterns, and 1 G1 isolate had a short pattern.Conclusion: G1P[8] was the most dominant strain of rotavirus causing diarrhoea in children in Yogyakarta. Age group, vomiting and stool mucous were associated with rotavirus positivity.

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Section: Discussionsupporting

confidence: 81%

Identification of Rotavirus Strains Causing Diarrhoea in Children under Five Years of Age in Yogyakarta, Indonesian

Nirwati

Hakim

Aminah³

et al. 2017

MJMS

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“…The literature concerning symptom severity in norovirus and rotavirus gastroenteritis is heterogeneous [42]. A number of previous studies found lower levels of disease severity in norovirus than in rotavirus gastroenteritis, and most of these were carried out in developed countries [7,[43][44][45][46][47]. In contrast, other studies found no significant differences between the severity of rotavirus and norovirus infections [48][49][50][51].…”

Section: Discussionmentioning

confidence: 99%

Epidemiology and clinical features of gastroenteritis in hospitalised children: prospective survey during a 2-year period in a Parisian hospital, France

Lorrot

Bon

Hajje

et al. 2010

Eur J Clin Microbiol Infect Dis

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International audienceRotavirus is recognised as the most important agent of severe acute gastroenteritis (AGE) in young children. In a 2-year prospective survey, we investigated the epidemiology and clinical features of the viral and bacterial pathogens in children hospitalised for AGE. The study was performed in a Parisian teaching hospital from November 2001 to May 2004. Clinical data were prospectively collected to assess the gastroenteritis severity (20-point Vesikari severity score, the need for intravenous rehydration, duration of hospitalisation). Stools were systematically tested for group A rotavirus, norovirus, astrovirus and adenovirus 40/41, sapovirus and Aichi virus and enteropathogenic bacteria. A total of 457 children (mean age 15.9 months) were enrolled. Viruses were detected in 305 cases (66.7%) and bacteria in 31 cases (6.8%). Rotaviruses were the most frequent pathogen (48.8%), followed by noroviruses (8.3%) and adenoviruses, astroviruses, Aichi viruses and sapoviruses in 3.5%, 1.5%, 0.9% and 0.4%, respectively. Cases of rotavirus gastroenteritis were significantly more severe than those of norovirus with respect to the Vesikari score, duration of hospitalisation and the need for intravenous rehydration. Rotaviruses were the most frequent and most severe cause in children hospitalised for AGE, and noroviruses also account for a large number of cases in this population

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“…Hastalık 4-8 günde kendini sınırlar 21 . Chen ve arkadaşları hastanede yatış sürelerini ortalama rota virüslerde ve adenovirüslerde 5'er gün olarak saptamışlardır 22 . Bizim çalışmamızda hastanede yatış süresi 3-5 gün arasında değişmekteydi.…”

Section: Kaynaklarunclassified

The ratio of pathogenic agent isolation in childhood gastroenteritis and its relevance to success in therapy

Küçük¹,

Göçmen²,

Balcı³

2011

Kafkas J Med Sci

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OBJECTIVE:To evaluate the current approach and management quality of childhood gastroenteritis in a secondary health center setting. Kafkas J Med Sci 2011; 1(1):8-12 • doi: 10.5505/kjms.2011.10820 Gastroenterit, iştahsızlık, bulantı ve kusma gibi bulgularla başlayan, değişik derecelerde ishal ile kendini gösteren gastrointestinal mukozanın enfl amatuar hastalığıdır. METHODS: Children diagnosed with gastroenteritis between January 1st and October 1st of 2010 were evaluated retrospectively by analysis of the parameters of age, gender, month of admission, laboratory fi ndings, hydration therapy and hospitalization. RESULTS: The study included 216 boys (58%) and 156 girls (42%

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Molecular Epidemiology and Clinical Manifestations of Viral Gastroenteritis in Hospitalized Pediatric Patients in Northern Taiwan

Cited by 72 publications

References 15 publications

Identification of Rotavirus Strains Causing Diarrhoea in Children under Five Years of Age in Yogyakarta, Indonesian

Identification of Rotavirus Strains Causing Diarrhoea in Children under Five Years of Age in Yogyakarta, Indonesian

Epidemiology and clinical features of gastroenteritis in hospitalised children: prospective survey during a 2-year period in a Parisian hospital, France

The ratio of pathogenic agent isolation in childhood gastroenteritis and its relevance to success in therapy

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