The three-dimensional flow of Water based Graphene Oxide (GO-W) and Ethylene Glycol based Graphene Oxide (GO-EG) nanofluids amongst the binary upright and parallel plates is considered. The unsteady movement of the nanofluid is associated with the porous medium and the uniform magnetic field is executed in the perpendicular direction of the flow field. The basic governing equations have been altered using the Von Karman transformation, including the natural convection in the downward direction. The solution for the modeled problem has been attained by means of optimal homotopy analysis method (OHAM). The influence of the physical parameters on the momentum boundary layer, pressure, and temperature fields is mainly focused. Moreover, the comparison of the GO-W and GO-EG nanofluids under the impact of physical constraints has been analyzed graphically and numerically. The imperative physical constraints of the drag force and heat transfer rate have been computed and discussed. The results have been validated using the error analysis and the obtained outcomes have been shown and discussed. The obtained results are compared with the numerical ND-Solve method. It is obtained that the increasing order of the iterations reduces the absolute error and the results go to the strong convergence. Moreover, the impact of the physical parameters is more precise in the GO-EG nanofluid due to its higher thermophysical properties. INDEX TERMS Water, Ethylene Glycol, Graphene Oxide, MHD, porous medium, two vertical and parallel plates, OHAM and numerical ND-solve techniques.