The nanofluids can be used in the subsequent precise areas like chemical nanofluids, environmental nanofluids, heat transfer nanofluids, pharmaceutical nanofluids, drug delivery nanofluids, and process/extraction nanofluids. In short, the number of engineering and industrial applications of nanofluid technologies, as well as their emphasis on particular industrial applications, has been increased recently. Therefore, this exploration is carried out to analyze the nanofluid flow past a rotating disk with velocity slip and convective conditions. The water-based spherical-shaped nanoparticles of copper, alumina, and titanium have been considered in this analysis. The modeled problem has been solved with the help of homotopic technique. Convergence of the homotopic technique is shown with the help of the figure. The role of the physical factors on radial and tangential velocities, temperature, surface drag force, and heat transfer rate are displayed through figures and tables. The outcomes demonstrate that the surface drag force of the water-based spherical-shaped nanoparticles of Cu, Al2O3, and TiO2 has been reduced with a greater magnetic field. The radial and tangential velocities of the water-based spherical-shaped nanoparticles of Cu, Al2O3, and TiO2, and pure water have been augmented via magnetic parameter. The radial velocity of the water-based spherical-shaped nanoparticle of Cu has been augmented via nanoparticle volume fraction, whereas reduced for the Al2O3 and TiO2 nanoparticles. The tangential velocity of the water-based spherical-shaped nanoparticles of Cu, Al2O3, and TiO2 has reduced via nanoparticle volume fraction. Also, the variations in radial and tangential velocities are greater for slip conditions as compared to no-slip conditions.