Myxoinflammatoric Fibroblastic Sarcoma in the Hand

Hohendorff, B.; Kurzen, P; Giger, A.; Stauffer, Edouard

doi:10.1016/j.jhsb.2007.01.008

Cited by 3 publications

(4 citation statements)

References 7 publications

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“…As such, we agree with Hohendorff et al [13] that X-rays are nonspecific. Moreover, other authors did not observe a common pattern of MRI findings, and this tumor may be confused with benign entities such as a ganglion cystis on unenhanced sequences [12,21].…”

Section: Discussionsupporting

confidence: 94%

“…To our knowledge, only 167 cases have been previously reported in international literature [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]. Ninety-five of these cases were reported by Meis-Kindblom and Kindblom [1] and Montgomery [3] in 1998.…”

Section: Discussionmentioning

confidence: 99%

“…Montgomery et al [3] and Hohendorff [13] reported that adjuvant therapy is not required. Meis-Kindblom and Kindblom [1] and Narvàez et al [21] suggested postoperative radiation therapy in selected cases.…”

Section: Discussionmentioning

confidence: 99%

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A rare case of acral myxoinflammatory fibroblastic sarcoma at the hand

2010

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One case of acral myxoinflammatory fibroblastic sarcoma is presented. Most of the soft tissue tumefactions of the distal extremities are benign. Sarcomas are rare and usually high grade. Acral myxoinflammatory fibroblastic sarcoma is a unique low-grade tumor described by Kindblom in 1998. This neoplasm has a propensity for digits, presents a low rate of metastasis and is characterized by a high rate of local multiple and aggressive recurrence. The clinical presentation, the frequent association with tenosynovitis and the extensive inflammatory infiltrate can lead to misdiagnosis by both the surgeon and the pathologist. Correct and early diagnosis depends on a good knowledge of histological and immunohistochemical findings. It is important to avoid recurrences recurring to an immediate wide excision of the tumor.

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Section: Discussionsupporting

confidence: 94%

Section: Discussionmentioning

confidence: 99%

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A rare case of acral myxoinflammatory fibroblastic sarcoma at the hand

2010

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“…Ambos géneros se encuentran afectados por igual 5 . Su forma de presentación es la de una masa en las extremidades, especialmente dedos, y habitualmente está incluida en el tejido celular subcutáneo, con un crecimiento lento y generalmente indolora [6][7][8] .…”

Section: Discussionunclassified

Sarcoma fibroblástico mixoinflamatorio acral: caso clínico y revisión bibliográfica

Jiménez¹,

Proubasta²,

Arriaga³

et al. 2014

Rev Iberoam Cir Mano

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Resumen: El sarcoma fibroblástico mixoinflamatorio es un tumor maligno de bajo grado de partes blandas, generalmente localizado en extremidades y que afecta a sujetos de mediana edad. Clínicamente, la lesión es infiltrativa, indolora y de curso evolutivo lento. Se presenta un caso que afecta la mano, haciendo una extensa revisión de la bibliografía, con especial atención a su diagnóstico y tratamiento.Palabras claves: Sarcoma, fibroblástico, mixoinflamatorio, mixoide, inflamatorio, acral. Acral Myxoinflammatory Fibroblastic Sarcoma: Case Report and Review of the LiteratureAbstract: Acral myxoinflammatory fibroblastic sarcoma is a rare low-grade malignant soft tissue tumor, usually observed in the extremities of middle-aged patients. Clinically, the lesion is infiltrating, pain-free and a slow progression. A case involving the hand is presented, doing an extensive review of the literatura, with particular attention to diagnosis and treatment.Key words: Sarcoma, fibroblastic, mysoinflammatory, myxoid, inflammatory, acral. Antonio García Jiménez C/ Mas Casanovas, 90 08025 Barcelona Email: agarciaji@santpau.catEl sarcoma fibroblástico mixoinflamatorio (SFMI) es un sarcoma de partes blandas muy poco común, de tipo multinodular y que se localiza con preferencia distalmente, motivo por el cual se añade el apelativo "acral" cuando asienta en manos y/o pies 1 . El tratamiento de elección es el quirúrgico, mediante la exéresis de la tumoración. Aunque dicho tumor suele ser de bajo grado, en ocasiones puede producir metástasis. Sin embargo, su principal problema es su alta incidencia de recidiva local 2 .El motivo del presente trabajo es describir un nuevo caso de SFMI, localizado en mano, y cuyo diagnóstico solo pudo determinarse después de su estudio anatomopatológico tras la resección quirúrgica. A partir de este caso, se realiza una extensa revisión sobre esta particular patología, con especial atención a su diagnóstico y tratamiento. CASO CLÍNICOSe trata de un varón de 31 años de edad, que acudió derivado de otro centro para estudio y tratamiento de una tumoración en la mano derecha de dos años de evolución. Según refiere, notó la aparición de una pequeña masa en la cara palmar de la mano, entre los dedos anular y meñique, de localización digitopalmar, indolora, y que fue aumentando de tamaño progresivamente en los últimos seis meses. Niega antecedente traumático.El examen físico reveló la presencia de una gran tumoración en la palma de la mano derecha, de consistencia blanda y que se extendía hacia la cara dorsal entre los espacios intermetacarpianos tercero y cuarto N Figura 1. Esta tumoración no era dolorosa a la palpación y no presentaba signos inflamatorios. Sin embargo, existía un déficit de flexión activa de los dedos meñique y anular, al existir un conflicto de espacio por el volumen de la misma.El estudio radiográfico simple fue normal y en la Resonancia Magnética (RM) se objetivó un proceso expansivo de partes blandes, situado en la profundidad de la aponeurosis palmar, que infiltraba la musculatura hipotena...

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A case of lung metastasis in myxoinflammatory fibroblastic sarcoma: analytical review of one hundred and thirty eight cases

Lombardi

Jovine

Zanini

et al. 2013

International Orthopaedics (SICOT)

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Purpose Myxoinflammatory fibroblastic sarcoma (MIFS) is a rare soft tissue tumour first identified at the end of the 1990s. This study presents our experience and literature reviews focusing on risk of recurrence. Methods Rizzoli Orthopaedic Institute database and literature were searched for patients with MIFS observed from 1997 to 2012. Data were analysed in a new database. Results Five patients underwent surgery at our institute, and 133 cases were retrieved from the literature. Not all clinicopathological data were available: 76/138 were men (55 %), median age was 45 [interquartile range (IQR) 34-56] years, median tumour size was three (IQR two to five) centimetres. Common sites of occurrence were hand (24 %), fingers (23 %) and foot (20 %). Pain was present at diagnosis in 14/82 patients (17 %), with a median duration of seven (IQR three to 12) months. Surgery was performed for a suspected benign tumour in 88 patients (74 %). Resection was incomplete in 45/ 71 cases (63 %); re-excision was performed in 32/45 (71 %). At a median follow-up of 26 months, 26/118 patients (22 %) developed recurrent disease; median time to recurrence was 15 months (IQR seven to 26). Actuarial relapse-free survival (RFS) at one, three and five years was 93 %, 72 % and 67 %, respectively. At univariate analysis, only symptom duration of six months or less was significantly associated with a worse RFS (p=0.046). Metastatic disease to lymph nodes and/or lungs was observed in four patients (3 %). Conclusions Clinicopathological findings confirm the lowgrade nature of MIFS. However, local recurrence occurs, and patients may be affected by aggressive forms with a potential for distant metastases. Follow-up is strongly advised.

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Myxoinflammatoric Fibroblastic Sarcoma in the Hand

Cited by 3 publications

References 7 publications

A rare case of acral myxoinflammatory fibroblastic sarcoma at the hand

A rare case of acral myxoinflammatory fibroblastic sarcoma at the hand

Sarcoma fibroblástico mixoinflamatorio acral: caso clínico y revisión bibliográfica

A case of lung metastasis in myxoinflammatory fibroblastic sarcoma: analytical review of one hundred and thirty eight cases

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