Nanocellulose as sustainable biomaterials for drug delivery

Das, Sudipta; Ghosh, Baishali; Sarkar, Keya

doi:10.1016/j.sintl.2021.100135

Cited by 78 publications

(40 citation statements)

References 205 publications

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“…Drug delivery systems refer to the advanced technologies used for targeted delivery and/or controlled release of therapeutic drugs [1]. In the past few decades, drug delivery systems have received much attention because they offer potential benefits, such as reducing side effects, improving therapeutic effects, and possibly reducing doses of drugs [2].…”

Section: Introductionmentioning

confidence: 99%

Nanocellulose-Based Composite Materials Used in Drug Delivery Systems

et al. 2022

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Nanocellulose has lately emerged as one of the most promising “green” materials due to its unique properties. Nanocellulose can be mainly divided into three types, i.e., cellulose nanocrystals (CNCs), cellulose nanofibrils (CNFs), and bacterial cellulose (BC). With the rapid development of technology, nanocellulose has been designed into multidimensional structures, including 1D (nanofibers, microparticles), 2D (films), and 3D (hydrogels, aerogels) materials. Due to its adaptable surface chemistry, high surface area, biocompatibility, and biodegradability, nanocellulose-based composite materials can be further transformed as drug delivery carriers. Herein, nanocellulose-based composite material used for drug delivery was reviewed. The typical drug release behaviors and the drug release mechanisms of nanocellulose-based composite materials were further summarized, and the potential application of nanocellulose-based composite materials was prospected as well.

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Section: Introductionmentioning

confidence: 99%

Nanocellulose-Based Composite Materials Used in Drug Delivery Systems

et al. 2022

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“…Mechanical treatment is the most common method for isolating CNF. However, other methods, such as enzymatic and chemical treatments, have also been documented [12,21]. High-pressure homogenization, ultrasonic fiber delamination, and ball-mining are the preferred approaches to obtaining CNF.…”

Section: Cellulose Nanofiber (Cnf)mentioning

confidence: 99%

“…Archromobacter, Acetobacter, Alcaligenes, Sarcina, Pseudomonas, and Rhizobium are the microbial sources capable of producing nanocellulose [14][15][16][17][18][19]. Maize cob, cotton, wheat bran, banana leaves, sugar beet, wood, potato tuber, and mulberry husks are potential plant sources for nanocellulose extraction [20,21]. CNC is primarily obtained by the acid hydrolysis of natural cellulose [22][23][24].…”

Section: Introductionmentioning

confidence: 99%

A Review of Properties of Nanocellulose, Its Synthesis, and Potential in Biomedical Applications

et al. 2022

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Cellulose is the most venerable and essential natural polymer on the planet and is drawing greater attention in the form of nanocellulose, considered an innovative and influential material in the biomedical field. Because of its exceptional physicochemical characteristics, biodegradability, biocompatibility, and high mechanical strength, nanocellulose attracts considerable scientific attention. Plants, algae, and microorganisms are some of the familiar sources of nanocellulose and are usually grouped as cellulose nanocrystal (CNC), cellulose nanofibril (CNF), and bacterial nanocellulose (BNC). The current review briefly highlights nanocellulose classification and its attractive properties. Further functionalization or chemical modifications enhance the effectiveness and biodegradability of nanocellulose. Nanocellulose-based composites, printing methods, and their potential applications in the biomedical field have also been introduced herein. Finally, the study is summarized with future prospects and challenges associated with the nanocellulose-based materials to promote studies resolving the current issues related to nanocellulose for tissue engineering applications.

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“…Cellulose-based materials advanced drug delivery [51,[223][224][225][226][227]. They can be conjugated with nanomaterials such as magnetic nanoparticles (MNPs) to offer multifunctional applications [228].…”

Section: Drug and Gene Delivery Using Cellulose-based Materialsmentioning

confidence: 99%

A Review on Cellulose-based Materials for Biomedicine

Abdelhamid¹,

Mathew²

2022

Preprint

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There are various biomaterials in nature, but none fulfills all the requirements. Cellulose, eco-friendly material-based biopolymers, have been advanced biomedicine to satisfy most market demand and circumvent many ecological concerns. This review aims to present an overview of the state of the art in cellulose's knowledge and technical biomedical applications. It included an extensive bibliography of recent research findings for fundamental and applied investigations. The chemical structure of cellulose allows modifications and simple conjugation with several materials, including nanoparticles, without tedious efforts. Cellulose-based materials were used for biomedicine applications such as antibacterial agents, antifouling, wound healing, drug delivery, tissue engineering, and bone regeneration. They advanced the applications to be cheap, biocompatible, biodegradable, easy for shaping and processing into different forms, with suitable chemical, mechanical and physical properties.

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Nanocellulose as sustainable biomaterials for drug delivery

Cited by 78 publications

References 205 publications

Nanocellulose-Based Composite Materials Used in Drug Delivery Systems

Nanocellulose-Based Composite Materials Used in Drug Delivery Systems

A Review of Properties of Nanocellulose, Its Synthesis, and Potential in Biomedical Applications

A Review on Cellulose-based Materials for Biomedicine

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