Nanoparticle fabrication of calcium oxide (CaO) mediated by the extract of red dragon fruit peels (<i>Hylocereus Polyrhizus</i>) and its application as inorganic–anti-microorganism materials

Ramli, Muliadi; Rossani, Ratu Balqis; Nadia, Yola; Darmawan, T; Febriani, .; Saiful, Saiful; Ismail, Yulia Sari

doi:10.1088/1757-899x/509/1/012090

Cited by 28 publications

(9 citation statements)

References 6 publications

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“…00-004-0777, it demonstrated a cubic structure without impurities. 20 , 27 , 44 , 45 In the XRD pattern of CaO, a few low-intensity calcite peaks (CaCO 3 ) illustrate rapid carbonation of CaO by atmospheric CO 2. 46 Upon codoping, the slightly shifted layer spacing to higher values is attributed to the homogeneous distribution of Ce and CNC between interlayers of pure CaO, which is consistent with the peak shift observed in XRD spectra.…”

Section: Resultsmentioning

confidence: 99%

Enhanced Photocatalytic Degradation with Sustainable CaO Nanorods Doped with Ce and Cellulose Nanocrystals: In Silico Molecular Docking Studies

et al. 2022

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This research work intends to evaluate the photoactivity of calcium oxide (CaO) nanorods (NRs) doped with cellulose nanocrystals (CNCs) and cerium (Ce). CNC-doped CaO and Ce/CNC codoped CaO were synthesized via the sol–gel technique. Structural, optical, morphological, physiochemical, phase constitution, and functional group evaluations were performed. The photodegradation of the prepared nanostructures was analyzed by observing photodegradation of a mixture of methylene blue and ciprofloxacin dye under light irradiation. The photocatalytic activity of the dye was drastically enhanced upon codoping in CaO. For both Escherichia coli and Staphylococcus aureus , statistically significant inhibitory zones ( p < 0.05) were achieved in the case of CNCs and pristine and codoped CaO. Furthermore, in silico molecular docking studies (MDS) were accomplished against DNA gyrase from nucleic acid biosynthesis and enoyl-[acyl-carrier-protein] reductase (FabI) from the fatty acid biosynthetic pathway to rationalize the possible mechanism behind these antibacterial activities.

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Section: Resultsmentioning

confidence: 99%

Enhanced Photocatalytic Degradation with Sustainable CaO Nanorods Doped with Ce and Cellulose Nanocrystals: In Silico Molecular Docking Studies

et al. 2022

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“…Buah naga merah (Hylocereus polyrhizus) merupakan jenis buah naga yang banyak ditemukan di Indonesia. 18 Bagian dari buah naga yang dimanfaatkan dalam penelitian ini ialah kulit buahnya. Kulit buah naga merah dipilih karena optimalisasi pemanfaatan kulit buah naga merah cenderung rendah, sehingga kulit buah naga merah hanya menjadi limbah organik dari setiap penggunaannya.…”

Section: Pendahuluanunclassified

Pengaruh Konsentrasi Ekstrak Kulit Buah Naga Merah terhadap Pertum-buhan Streptococcus mutans pada Sediaan Obat Kumur (Uji Invitro)

Ariyani

Armalina

Purbaningrum

2021

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Caries could be minimized by reducing plaque accumulation with an antiseptic mouthwash. However, chlorhexidine 0,2%, the gold standard mouthwash, is known to have side effects. This has led to the innovation of an alternative herbal-based mouthwash that has antibacterial properties; one of the possible natural material is red dragon fruit peels. This study was aimed to prove the effect of red dragon fruit peel extract as mouthwash prepared in several concentrations to inhibit the growth of Streptococcus mutans. This was a quasi-experimental study with the post test control group design. There were six sample groups, namely mouthwash with extract concentration of 6.25%, 12.5%, 25%, and 50%, negative control (aquadest), and positive control (chlorhexidine 0.2%). The antibacterial assessment was done by using the well diffusion method calculating the inhibition zone formed around the wellbore. Data were analyzed by using the Kruskal Wallis test and the Mann Whitney Post Hoc test. The results showed that the average inhibition zones formed by extract mouthwash of 6.25%, 12.5%, 25%, 50% were 3.18 mm, 5.13 mm, 7.30 mm, and 11.01 mm respectively, and by positive control was 14.65 mm. There were significant differences between each treatment group. All concentrations of red dragon fruit peel extract in mouthwash could inhibit effectively the growth of Streptococcus mutans although not as effective as the positive control. In conclusion, red dragon fruit peel extract mouthwash could inihibit the growth of Streptococcus mutans.Keywords: mouthwash; red dragon fruit peel; Streptococcus mutans; antibacterial effect Abstrak: Karies dapat diminimalisasi dengan mengurangi akumulasi plak menggunakan obat kumur antiseptik. Obat kumur chlorhexidine 0,2% merupakan obat kumur baku emas namun memiliki efek samping. Hal tersebut memunculkan inovasi untuk mencari alternatif obat kumur berbahan dasar herbal yang memiliki sifat antibakteri; salah satunya ialah kulit buah naga merah. Penelitian ini bertujuan membuktikan pengaruh ekstrak kulit buah naga merah dalam obat kumur dengan beberapa konsentrasi untuk menghambat pertumbuhan Streptococcus mutans penyebab karies. Jenis penelitian ialah quasi experimental dengan desain post test only group control design. Terdapat enam kelompok sampel yaitu obat kumur konsentrasi ekstrak 6,25%, 12,5%, 25%, 50%, kontrol (-) akuades, dan kontrol (+) chlorhexidine 0,2%. Uji antibakteri menggunakan metode difusi sumuran dengan menghitung zona hambat yang terbentuk di sekitar lubang sumuran. Uji statistik menggunakan Kruskal Wallis dan uji post hoc Mann Whitney. Hasil penelitian mendapatkan rerata zona hambat yang terbentuk dari obat kumur konsentrasi ekstrak 6,25%, 12,5%, 25%, 50% ialah 3,18 mm, 5,13 mm, 7,30 mm, 11,01mm, dan kelompok kontrol(+) ialah 14,56 mm. Perbedaan bermakna terdapat pada setiap kelompok perlakuan. Setiap konsentrasi ekstrak kulit buah naga merah dalam obat kumur berpengaruh menghambat pertumbuhan bakteri Streptococcus mutans, namun belum sebaik kontrol (+). Simpulan penelitian ini ialah ekstrak kulit buah naga merah dalam obat kumur berpengaruh menghambat pertumbuhan bakteri Streptococcus mutans.Kata kunci: obat kumur; kulit buah naga merah; Streptococcus mutans; efek antibakteri

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“…It is also used to remove SO 2 or other sulfur containing pollutants from the exhaust gases [12]. Recently, the ultrafine particles of CaO are used as bactericide and antibacterial agents for controlling the microorganisms and absorbent [8,[13][14][15]. The common human diseases like typhoid, diarrhea, cholera, intestinal infections, etc., are due to the infection from water born bacterial pathogens.…”

Section: Introductionmentioning

confidence: 99%

“…It has been reported that solution based chemical methods has excellent tendency to control the size, shape, distribution and other properties of the end products [4]. CaO and Ca(OH) 2 nanoparticles are reported to synthesized by sol-gel method, thermal decomposition, precipitation, hydrothermal, microwave-assisted method, etc., [3,9,[11][12][13][14][15][16][17][18][19]. Among all these methods, direct precipitation is simple, cost-effective, reproductive and rapid technique for nanoparticles synthesis [20][21][22].…”

Section: Introductionmentioning

confidence: 99%

Structural, Optical and Antibacterial Response of CaO Nanoparticles Synthesized via Direct Precipitation Technique

Kumar¹,

Sharma²,

Pradhan³

et al. 2021

Nano BioMed ENG

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Calcium oxide (CaO) is a promising material that works as a glass constituent, catalyst, toxicwaste remediation, poisonous gas absorbent, industrial refectory element for metal smelting, paper bleaching, sulfur neutralization in sugar, cosmetics and drug delivery mediator. This work proposes the synthesis of CaO nanoparticles by direct precipitation technique using an aqueous solution of calcium chloride and sodium hydroxide precursors. The synthesized nanoparticles are characterized for the structure, morphology, chemical composition and optical behavior using Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), field effect scanning electron microscopy (FE-SEM), energy dispersive X-ray spectroscopy (EDS), and diffuse reflectance spectroscopy. The XRD results show that the CaO nanoparticles have been synthesized in a cubic crystalline structure with the average crystallite size of about 13 nm and display aggregated morphology of nanoclusters. The presence of distinct peaks in the FTIR and EDS spectra reveal that the nanoparticles are successfully formed from the chemical recipe of the precipitation process. The optical bandgap has been estimated from the Kubelka-Munk plot and found to be 3.48 eV. The antibacterial activity of CaO nanoparticles has been tested by the well diffusion technique and observed that it shows good antibacterial action against the gram-negative bacterial strains.

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Nanoparticle fabrication of calcium oxide (CaO) mediated by the extract of red dragon fruit peels (Hylocereus Polyrhizus) and its application as inorganic–anti-microorganism materials

Cited by 28 publications

References 6 publications

Enhanced Photocatalytic Degradation with Sustainable CaO Nanorods Doped with Ce and Cellulose Nanocrystals: In Silico Molecular Docking Studies

Enhanced Photocatalytic Degradation with Sustainable CaO Nanorods Doped with Ce and Cellulose Nanocrystals: In Silico Molecular Docking Studies

Pengaruh Konsentrasi Ekstrak Kulit Buah Naga Merah terhadap Pertum-buhan Streptococcus mutans pada Sediaan Obat Kumur (Uji Invitro)

Structural, Optical and Antibacterial Response of CaO Nanoparticles Synthesized via Direct Precipitation Technique

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