Norditerpenoid alkaloids from Consolida thirkeana and Consolida sulphurea

Meriçli, Ali H.; Yazici, Secil; Özkan, Esra Eroğlu; Şen, Burcu Gezer; Kurtoğlu, Sezin; Özçelik, Hasan; Zapp, Josef; Kiemer, Alexandra K.; Meriçli, Filiz

doi:10.1007/s10600-012-0299-9

Cited by 7 publications

(4 citation statements)

References 8 publications

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“…The literature search showed that this phytochemical study on C. thirkeana, a medicinally important plant belonging to the Ranunculaceae family, is the first report except for some studies [4,18].…”

Section: Resultsmentioning

confidence: 99%

Gas Chromatography-Mass Spectrometry (Gc-Ms) Analysis of Consolida Thirkeana Extract

Tok¹,

YAYLA²

2022

Ankara Universitesi Eczacilik Fakultesi Dergisi

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Objective: Consolida thirkeana (Boiss.) Bornm. (Ranunculaceae) is considered endemic to Turkey and identified by pale lilac flowers, sessile follicles, and laciniae linear leaves. The genus Consolida can often be confused morphologically with Delphinium, in this respect, members of the genus Consolida need chemotaxonomic interest. In this study, the phytochemical content of C. thirkeana was clarified by GC/MS analysis.Material and Method: The plant material was collected from Ayaş (Ankara/Turkey). A voucher specimen was deposited in the Ankara University Faculty of Pharmacy Herbarium. The aerial part of the plant was powdered in a grinder. The powdered plant parts were macerated with methanol. The GC-MS analysis of extracts was performed using an Agilent 6890 gas chromatograph equipped with an Agilent 5973N quadrupole mass spectrometer (Agilent, USA). Mass Hunter software (Qualitative Analysis B.07.00) and the NIST Mass Spectral Library (2014) were used for determining and identifying compounds.Result and Discussion: The analysis results of this study showed the presence of 15 compounds in C.

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Section: Resultsmentioning

confidence: 99%

Gas Chromatography-Mass Spectrometry (Gc-Ms) Analysis of Consolida Thirkeana Extract

Tok¹,

YAYLA²

2022

Ankara Universitesi Eczacilik Fakultesi Dergisi

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“…According to our previous work, many alkaloids have been isolated from Delphinium grandiflorum [3,4]. The title compound, ajacisine D monohydrate, is one of the diterpenoid alkaloids which have been proved to be the main chemical components of genus Delphinium [5,6]. These diterpenoid alkaloids have complex structure skeletons and posess multiple biological activities such as anastalsis, antibacterial activity [7][8][9][10].…”

Section: Commentmentioning

confidence: 99%

Crystal structure of ajacisine D monohydrate, C₃₀H₄₄N₂O₉

Zhao

et al. 2019

Zeitschrift Für Kristallographie - New Crystal Structures

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“…As a traditional Chinese medicine, the roots of D. ajacis are applied to treat stomachache, and the seeds are used to treat edema and asthma [2]. Previous phytochemical investigations have shown that the genus Delphinium is rich in alkaloids [3,4], flavonoids [5], and fatty acids [6]. Modern pharmacological studies have displayed that the diterpenoid alkaloids of the genus Delphinium possess cytotoxic [7,8] and antifungal [9] activities.…”

Section: Introductionmentioning

confidence: 99%

Diterpenoid Alkaloids from Delphinium ajacis and Their Anti-RSV Activities

et al. 2016

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Five new diterpenoid alkaloids, ajacisines A-E (-), were isolated from , along with seven known alkaloids (-). On the basis of their spectral data (IR, UV, HR-ESI-MS, 1D and 2D NMR) and chemical properties, the structures of compounds - were identified. All isolated compounds were evaluated for their antiviral activities against respiratory syncytial virus, and compounds- and exhibited moderate to weak effects with IC values of 75.2 ± 1.1, 35.1 ± 0.6, 10.1 ± 0.3, and 50.2 ± 0.5 µM, respectively.

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Norditerpenoid alkaloids from Consolida thirkeana and Consolida sulphurea

Cited by 7 publications

References 8 publications

Gas Chromatography-Mass Spectrometry (Gc-Ms) Analysis of Consolida Thirkeana Extract

Gas Chromatography-Mass Spectrometry (Gc-Ms) Analysis of Consolida Thirkeana Extract

Crystal structure of ajacisine D monohydrate, C₃₀H₄₄N₂O₉

Diterpenoid Alkaloids from Delphinium ajacis and Their Anti-RSV Activities

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Norditerpenoid alkaloids from Consolida thirkeana and Consolida sulphurea

Cited by 7 publications

References 8 publications

Gas Chromatography-Mass Spectrometry (Gc-Ms) Analysis of Consolida Thirkeana Extract

Gas Chromatography-Mass Spectrometry (Gc-Ms) Analysis of Consolida Thirkeana Extract

Crystal structure of ajacisine D monohydrate, C30H44N2O9

Diterpenoid Alkaloids from Delphinium ajacis and Their Anti-RSV Activities

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Crystal structure of ajacisine D monohydrate, C₃₀H₄₄N₂O₉