Occurrence of oxidative stress in dairy cows seropositives for Brucella abortus

Perin, Gessica; Fávero, Juscivete F.; Severo, Diego Rodrigo Torres; Silva, Aniélen D.; Machado, Gustavo; Araújo, Hugo L. de; Lilenbaum, Walter; Morsch, Vera Maria; Schetinger, Maria Rosa Chitolina; Jordão, R. S.; Stefani, Lenita M.; Bottari, Nathieli B.; Silva, Aleksandro S. Da

doi:10.1016/j.micpath.2017.06.043

Cited by 14 publications

(12 citation statements)

References 43 publications

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“…The increase in CAT levels in leptospiral infected animals might be because the body raised CAT levels as the first endogenous defense to neutralize ROS and compensate for the damage caused by the infectious process 36 . In contrast to earlier findings, no evidence of increases in CAT activity were found in cattle with Brucella abortus 37 …”

Section: Discussioncontrasting

confidence: 72%

“…36 In contrast to earlier findings, no evidence of increases in CAT activity were found in cattle with Brucella abortus. 37 Plasma and serum glutathione peroxidase (GPx) activity is of good diagnostic value in most diseases associated with renal impairment. 38 In this present study, serum GPx activities were higher in leptospiral infected horses than in healthy horses.…”

Section: Discussionmentioning

confidence: 99%

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The effect of natural infection with differentLeptospira interrogansserovars on oxidative stress biomarkers and acute‐phase responses in horses and cattle

Niroomandi

Maleki

Abdollahpour

et al. 2022

Veterinary Clinical Pathol

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Leptospirosis is one of the important zoonotic bacterial diseases with a worldwide distribution that is often subclinical. We aimed to investigate the oxidant/antioxidant balance and acute‐phase response in naturally infected horses and cattle with Leptospira interrogans. A total of 600 serum samples from horses and cattle were examined for L. interrogans antibodies using the microscopic agglutination test to determine anti‐Leptospira IgG antibodies against a panel of eight important Leptospira antigens in Iran. Then, serum total antioxidant capacity, catalase, glutathione peroxidase, and malondialdehyde activities, and nitric oxide, total protein, serum amyloid A, haptoglobin, and albumin concentrations were measured in seropositive and seronegative samples. Serum catalase activities and malondialdehyde, serum amyloid A, and haptoglobin ‌concentrations in seropositive cattle and horses were significantly higher (P < .05) than in those that were seronegative. Antibody titers increased from 1:100 to ≥1:200 in cattle with L. interrogans infection, resulting in a decrease in the serum total antioxidant capacity (P < .05), an increase in serum glutathione peroxidase (P < .01) activity and nitric oxide (P < .05) , serum amyloid A (P < .01), and haptoglobin (P < .05) concentrations. Following the increase in the agglutinating antibody titers in horses infected with L. interrogans, the serum total antioxidant capacity (P < .01) decreased, and serum nitric oxide (P < .05), malondialdehyde (P < .05), and serum amyloid A (P < .01) concentrations were increased. In this study, horses and cattle had extensive changes in oxidant/antioxidant equilibrium and acute‐phase protein concentrations when infected with L. interrogans. We also demonstrated a direct link between antibody titers and the type of leptospiral serovar using serum oxidative and inflammatory markers.

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Section: Discussioncontrasting

confidence: 72%

Section: Discussionmentioning

confidence: 99%

The effect of natural infection with differentLeptospira interrogansserovars on oxidative stress biomarkers and acute‐phase responses in horses and cattle

Niroomandi

Maleki

Abdollahpour

et al. 2022

Veterinary Clinical Pathol

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“…This similarity can be attributed to the rise in use of SOD in order to eliminate the harmful effects of increasing oxidants in the anthrax vaccine group. Contrary to these findings, it has been reported that there is an increase in SOD level in calves with brucella (Perin et al 2017) and septicemia (Meral et al 2017) and in cattle infected with Taenia saginata (Łuszczak et al 2011), as well as ethionine administered cattle (Abd Ellah et al 2009). Consequently, it can be suggested that there may be other factors affecting SOD level.…”

Section: Discussionmentioning

confidence: 87%

The Effect of Vitamin C on Oxidant and Antioxidant Parameters in Anthrax Vaccine Administered Cattle

Doğan

Merhan

Erdağ

et al. 2021

Van Veterinary Journal

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In this study, the effects of Vitamin C on oxidative stress in anthrax vaccinated cattle were investigated. The research was performed on 40 healthy cattle without any race and gender difference, and aged 6-8 months that were not anthrax vaccinated. The cattle were divided into four equal groups. The first group was determined as the control group. 1 ml anthrax vaccine was administered to the second group, 1 ml anthrax vaccine and 5 mg/kg dose of vitamin C was administered to the third group, and vitamin C was administered to the fourth group at a dose of 5 mg/kg. Blood collection were collected and serum samples were extracted just before the vaccination and drug administration (0 th day) and on the 2 nd , 14 th and 28 th days after the administration. Nitric Oxide (NO), Malondialdehyde (MDA), Superoxide Dismutase (SOD) and Catalase (CAT) levels of serum samples were evaluated. It was found that the MDA and NO levels significantly increased (P<0.05), and the amount of SOD and CAT decreased in the vaccine group on the 2 nd , 14 th and 28 th days compared to the control group. It was determined that the MDA and NO levels in the vaccine-vitamin groups on the 2 nd , 14 th and 28 th days decreased insignificantly (P> 0.05) compared to the vaccine group. It can be asserted that the use of vitamin C in combination with anthrax vaccine in cattle would be beneficial in terms of reducing oxidative stress.

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“…TAC values were found to be statistically significantly lower and TOC and OSI values were found to be significantly higher, compared to the control group reported in cattle with brucellosis (Karaagac et al 2011;Merhan et al 2017). Brucella abortus-infected cattle reported exposure of Brucella-infected bugs to oxidative stress (Kataria et al 2012;Perin et al 2017).…”

Section: Discussionmentioning

confidence: 99%

The assessment of the protein profiles and oxidant/antioxidat status in conjunctival Brucella melitensis Rev1 vaccinated sheep

Çiftçi

Çiftci

2021

Etlik Veteriner Mikrobiyoloji Dergisi

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Brucellosis is a zoonotic and economically significant animal disease worldwide. The most frequently used vaccine to avoid brucellosis in small ruminants is the Rev.1 conjunctival Brucella melitensis vaccine. The aim of this study was to investigate the effects of B.melitensis Rev.1 conjunctival vaccine on total protein, albumin, globulin levels, protein profiles and oxidant/antioxidant status in sheep. Ten sheep were used as animal material for this purpose. The bloods taken before vaccination were used as negative control. The sera obtained one month after administration of single dose B.melitensis vaccine were used as experimental materials. The spectrophotometric method estimated total protein, albumin, globulin levels, total antioxidant capacity (TAS), and total oxidant capacity (TOS). Protein profile was determined by sodium-dodecyl-sulphate and native-polyacrylamide gel electrophoresis methods. It was determined that total protein and globulin levels increased slightly in sero positive sheep (P>0.05). There was no difference for protein profiles in both electrophoresis methods. The band densities of albumin decreased but gamma globulin increased slightly after vaccination. TAS levels decreased significantly (P<0.05), but TOS levels increased slightly (P>0.05). In conclusion, Rev.1 conjunctival Brucella vaccine was thought to be safe to use to prevent Brucellosis, and the addition of antioxidant after vaccination can reduce oxidative stress.

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Occurrence of oxidative stress in dairy cows seropositives for Brucella abortus

Cited by 14 publications

References 43 publications

The effect of natural infection with differentLeptospira interrogansserovars on oxidative stress biomarkers and acute‐phase responses in horses and cattle

The effect of natural infection with differentLeptospira interrogansserovars on oxidative stress biomarkers and acute‐phase responses in horses and cattle

The Effect of Vitamin C on Oxidant and Antioxidant Parameters in Anthrax Vaccine Administered Cattle

The assessment of the protein profiles and oxidant/antioxidat status in conjunctival Brucella melitensis Rev1 vaccinated sheep

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