Optimizing the method to calculate right ventricular ejection fraction from first-pass data acquired with a multicrystal camera

Johnson, Lynne L.; Lawson, Mark A.; Blackwell, Gerald G.; Tauxe, E. Lindsey; Russell, Kristi; Dell’Italia, Louis J.

doi:10.1016/s1071-3581(05)80024-8

Cited by 15 publications

(8 citation statements)

References 18 publications

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“…RV EF measured using this technique has been shown to compare well with measurements from MRI [6]. However, the problem of atrial overlap remains, and in many cases delineation of the right ventricle can be difficult.…”

Section: Introductionmentioning

confidence: 82%

“…The gold standard for measurement of RV EF is generally held to be magnetic resonance imaging (MRI) [5,6,7], although reproducibility can be a problem even with this technique [8]. In addition, MRI is very expensive and may be technically difficult in some patients (e.g.…”

Section: Introductionmentioning

confidence: 99%

“…However, overlap of counts from other cardiac chambers is an important problem with this technique, and results are generally unreliable [6,7,9].…”

Section: Introductionmentioning

confidence: 99%

“…In addition, first-pass acquisition can be technically challenging, since it depends strongly on adequate venous access, good bolus injection and accurate camera positioning. Even under research conditions, 15%-20% of first-pass scans will typically be excluded for technical reasons [6,11].…”

Section: Introductionmentioning

confidence: 99%

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Determination of right ventricular ejection fraction from reprojected gated blood pool SPET: comparison with first-pass ventriculography

et al. 2001

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Gated blood pool (GBP) studies are widely available and relatively inexpensive. We have previously published a simple and convenient method for measuring left ventricle ejection fraction (EF) with increased accuracy from single-photon emission tomography (SPET) GBP scans. This paper describes an extension of this method by which right ventricular EF may also be measured. Gated SPET images of the blood pool are acquired and re-oriented in short-axis slices. Counts from the left ventricle are excluded from the short-axis slices, which are then reprojected to give horizontal long-axis images. Time-activity curves are generated from each pixel around the right ventricle, and an image is created with non-ventricular pixels "greyed out". This image is used as a guide in drawing regions of interest around the right ventricle on the end-diastolic and end-systolic long-axis images. In 28 patients, first-pass ventriculography studies were acquired followed by SPET GBP scans. The first-pass images were analysed a total of four times by two observers and the SPET images were analysed three times each by two observers. The agreement between the two techniques was good, with a correlation coefficient of 0.72 and a mean absolute difference between first-pass and reprojected SPET EFs of 4.8 EF units. Only four of the 28 patients had a difference of greater than 8 EF units. Variability was also excellent for SPET right ventricular EF values. Intra-observer variability was significantly lower for SPET than for first-pass EFs: standard error of the estimate (SEE)=5.1 and 7.3 EF units, respectively (P<0.05). Inter-observer variability was comparable in the two techniques (SEE=5.2 and 6.9 EF units for SPET and first-pass ventriculography, respectively).

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Section: Introductionmentioning

confidence: 82%

Section: Introductionmentioning

confidence: 99%

“…However, overlap of counts from other cardiac chambers is an important problem with this technique, and results are generally unreliable [6,7,9].…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Determination of right ventricular ejection fraction from reprojected gated blood pool SPET: comparison with first-pass ventriculography

et al. 2001

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“…For accurate measurement of the RVEF, the first-pass RNA technique is preferred [28]. This technique shows promise as an accurate method for measurement of the RVEF and has potential clinical applicability in confirming the diagnosis of RV failure in the presence of high right-sided filling pressures and as an objective method to follow the effect of a treatment modality on pulmonary hypertension [29].…”

mentioning

confidence: 99%

Use of noninvasive tools in primary pulmonary hypertension to assess the correlation of right ventricular function with functional capacity and to predict outcome

Zafrir

Zingerman

Solodky

et al. 2006

Int J Cardiovasc Imaging

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Association between right heart dimensions and muscle performance and cardiorespiratory capacity in strength and endurance athletes

et al. 2021

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Our purpose was to investigate the association between right heart dimensions and muscle performance and cardiorespiratory capacity in athletes. We selected 90 men with a mean age of 33.0 ± 8.0 years: strength group (SG), 30 bodybuilders; endurance group (EG), 30 endurance athletes; and control group (CG), 30 healthy non‐athletes. Comprehensive echocardiography and radionuclide angiography allowed the cardiac evaluation. VO2peak was assessed by cardiopulmonary testing, muscle strength by the one‐repetition maximum test (1RM) and the relative strength (RS), and muscle endurance by the maximum repetitions test (MR) with 50% of 1RM. In SG was observed an association between right ventricle (RV) basal diameter and RS bench press (R2 = .188 β = 0.486 P = .017) and between right atrium (RA) area and MR leg press (R2 = .257 β = 0.143 P = .004). In EG was observed an association between RV basal diameter and VO2peak (R2 = .299 β = 0.026 P = .002) and between RA area and VO2peak (R2 = .417 β = 0.092 P ≤ .001). In conclusion, our data suggest that there is an association between right heart dimensions and muscle performance and cardiorespiratory capacity; moreover, muscle strength seems important for understanding cardiac adaptations to training.

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Optimizing the method to calculate right ventricular ejection fraction from first-pass data acquired with a multicrystal camera

Cited by 15 publications

References 18 publications

Determination of right ventricular ejection fraction from reprojected gated blood pool SPET: comparison with first-pass ventriculography

Determination of right ventricular ejection fraction from reprojected gated blood pool SPET: comparison with first-pass ventriculography

Use of noninvasive tools in primary pulmonary hypertension to assess the correlation of right ventricular function with functional capacity and to predict outcome

Association between right heart dimensions and muscle performance and cardiorespiratory capacity in strength and endurance athletes

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