Orbital Volume Augmentation After Injection of Human Orbital Adipose-Derived Stem Cells in Rabbits

Lee, Jae Yeun; Lee, Kwang Hyoung; Shin, Hyun Min; Chung, Kyeong Woo; Kim, Gwang Il; Lew, Helen

doi:10.1167/iovs.12-11210

Cited by 13 publications

(7 citation statements)

References 25 publications

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“…[51][52][53] Many animal models have been tried to find the best process of lipofilling. [54][55][56] However, among the animal models, there is no useful posttraumatic model. Further studies are needed in this field.…”

Section: Compositesmentioning

confidence: 99%

Materials to facilitate orbital reconstruction and soft tissue filling in posttraumatic orbital deformaties

Ye¹,

Sun²,

Zhang³

et al. 2016

PAR

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Posttraumatic orbital reconstruction has been a challenging mission for decades in craniomaxillofacial surgery. Complications like enophthalmos, diplopia and gaze obstacles emerge when orbital trauma occurs, affecting people's daily life as well as their appearance. Advances in technology and research gained through years of experience has provided us with a greater understanding of the changes following trauma, as well as providing us with a variety of filling materials that we can choose from to handle the deformities. However, the best type of material for repair of orbital deformities remains controversial. This paper reviewed approximately 60 articles discussing materials used in orbital reconstruction or soft tissue defect filling in the past years, with the aim of giving a comprehensive overview of the advantages and disadvantages of materials used in this field so as to help surgeons to make a better choice.

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Section: Compositesmentioning

confidence: 99%

Materials to facilitate orbital reconstruction and soft tissue filling in posttraumatic orbital deformaties

Ye¹,

Sun²,

Zhang³

et al. 2016

PAR

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“…It is known that loss of TOFV due to any cause causes eyelid retraction or proptosis that requires reconstruction to restore functional anatomy and aesthetic facial appearance, and in several studies (20,21) orbital fat volume augmentation is discussed. In the present study, the average TOFV of women was significantly greater than that of men.…”

Section: Unstandardized Coefficients --------------------------------mentioning

confidence: 99%

Exploration of orbital and orbital soft-tissue volume changes with gender and body parameters using magnetic resonance imaging

Erkoç

Öztoprak

Gümüş

et al. 2015

Experimental and Therapeutic Medicine

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Abstract. The aim of the present study was to examine the total orbital volume (TOV) and total orbital fat volume (TOFV) in normal orbits in different age groups and to investigate the correlation of these measurements with age, gender and body parameters by magnetic resonance imaging (MRI). MRI data were acquired retrospectively from a total of 1,453 subjects divided into five age groups with 10-year intervals. The TOV and TOFV were measured using T1-weighted MRI for each subject and body parameters were also obtained. The measurements demonstrated that TOV increased with age and that the volume was larger in men than in women. While weight and height exhibited positive correlations with TOV in male and female subjects in the 20-29, 30-39 and 40-49-year-old age groups, only weight showed a positive correlation with TOV in female subjects in the 50-59 and 60-69-year-old age groups. However, TOFV increased by age in all groups and the increments were larger in women than in men. These results provide basic information about the effect of age, gender and body parameters on TOV and TOFV. The variations in TOV are associated with orbital soft-tissues changes rather than with TOFV.

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“…The authors showed that injection of stem cells versus a control created globe proptosis that could be maintained for 12 weeks. 28 In our particular study, the rabbit fat was not isolated for stem cells, but this is one avenue in the future that could potentially lead to increased survival. The autologous fat obtained from each rabbit was notably more fibrous in nature than that obtained from humans.…”

Section: Discussionmentioning

confidence: 99%

Augmentation of Intraorbital Volume with Fat Injection

Brown

Lee

Zwiebel

et al. 2014

Plastic and Reconstructive Surgery

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Orbital Volume Augmentation After Injection of Human Orbital Adipose-Derived Stem Cells in Rabbits

Abstract: Thus, transplantation of hoADSCs with HAG is a safe and effective technique for orbital fat volume expansion. This is a new and promising method for orbital reconstruction and aesthetic orbital volume augmentation.

Cited by 13 publications

References 25 publications

Materials to facilitate orbital reconstruction and soft tissue filling in posttraumatic orbital deformaties

Materials to facilitate orbital reconstruction and soft tissue filling in posttraumatic orbital deformaties

Exploration of orbital and orbital soft-tissue volume changes with gender and body parameters using magnetic resonance imaging

Augmentation of Intraorbital Volume with Fat Injection

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