“…With the rapid evolution of global Internet, cloud computing, and 5G communication technologies, network traffic has experienced exponential growth, resulting the I/O channel capacity insufficient to meet the even-increasing demand [1,2]. To satisfy the stringent bandwidth requirement while improving the spectral efficiency, IEEE 802.3bs recommends PAM4 signaling to fulfill 200/400 Gb/s Ethernet by employing 4×50 Gb/s and 8×50 Gb/s multi-channel links [3,4]. The PAM4 signaling encodes the most significant bit (MSB) and the least significant bit (LSB), into one single symbol, thus enhancing the spectral efficiency and mitigating the bandwidth limitation for both channel and front-end circuit [5,6].…”