This study discusses local governments' opportunities and challenges in practising paradiplomacy in the Indo-Pacific region. A country's central government owns the authority to practice international relations, and local governments also own this authority through paradiplomacy practices. This study uses qualitative research methods by searching for theoretical references relevant to cases or problems found in various literature, mainly scientific journals, books, reports, and actual and trusted news on the internet. This paper aims to reveal local governments' opportunities and challenges in paradigmatic practice, especially in the Indo-Pacific region. From the analysis results, the practice of paradiplomacy in the Indo Pacific. This paper aims to reveal local governments' opportunities and challenges in paradiplomacy practice, especially in the Indo-Pacific region. From the analysis results, the practice of paradiplomacy in the Indo-Pacific is quite good but not maximised because many paradiplomacy practices reach the MoU stage. In contrast, they have not reached the program implementation frame. Generally, the Indo-Pacific region's opportunities for the practice of paradiplomacy are quite large because the regions in the Indo-Pacific region have many similarities, which is one of the crucial indicators in the practice of paradiplomacy.