Peningkatan asupan kalsium menghambat penurunan kepadatan tulang pada perempuan pascamenopause

Hayati, Sarah; Herwana, Elly

doi:10.18051/jbiomedkes.2018.v1.145-151

Cited by 5 publications

(5 citation statements)

References 8 publications

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“…Efek ketidakseimbangan tulang akan memengaruhi remodeling atau kerapuhan tulang yang disebabkan oleh jumlah dan aktivitas sel osteoklastik yang melebihi jumlah dan aktivitas sel osteoblas (sel pembentuk tulang) sehingga berisiko osteoporosis (Hayati, 2018). Penurunan kepadatan tulang merupakan masalah kesehatan yang disebabkan oleh perubahan struktur mikro tulang yang pada akhirnya membuat seseorang rentan mengalami patah tulang.…”

Section: Pendahuluanunclassified

Hubungan Asupan Kalsium dan Indeks Massa Tubuh dengan Kepadatan Tulang pada Wanita Usia Subur

Aini¹,

Pratiwi²,

Dewi³

et al. 2022

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In women of childbearing age, the rate of bone formation will decrease gradually. If a bone formation is reduced continuously then it can cause osteoporosis. Insufficient calcium intake and abnormal body mass index can also cause reduced bone density. The purpose of this study was to analyze the correlation between calcium intake and body mass index with bone density in women of childbearing age in the Medical Faculty Universitas Lampung in 2021. This cross-sectional study of 80 respondents consisting of lecturers, employees, and students aged 20-45 years who were selected by purposive sampling was carried out in November-December 2021. Demographic data, Semi Qualitative-Food Frequency Questionnaire (SQ-FFQ), Kris digital scales 9360A, microtoise GEA, and Quantitative Ultrasound (QUS) were used to measure all variables. Spearmen Correlation Test with a significant level of p-value<0.05 was used to see the relationship between variables. The results of the univariate analysis showed that the majority of respondents were aged 20-25 years (76.2%) and college students (78.8%). The average intake of calcium and body mass index was 709.2 and 21.2 and 31 respondents (38.8%) had osteoporosis. The results of the bivariate analysis showed a positive and significant correlation between calcium intake and bone density (p-value=0.000, r=0.687) and bone body mass index with bone density (p-value=0.000, r=0.596). The conclusion, there was a positive and significant correlation between calcium intake and body mass index with bone density in women of childbearing age in the Medical Faculty of Universitas Lampung in 2021.Â

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Section: Pendahuluanunclassified

Hubungan Asupan Kalsium dan Indeks Massa Tubuh dengan Kepadatan Tulang pada Wanita Usia Subur

Aini¹,

Pratiwi²,

Dewi³

et al. 2022

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“…Besides vitamins, minerals were also inadequate. Zinc, calcium, and iron were all insufficient and could be associated with the risk of low immune status, cognitive function, anemia, and osteoporosis [32,[39][40][41][42]. However, one mineral exceeded the daily recommended allowance-sodium [31].…”

Section: Nutrient Intakementioning

confidence: 99%

The Road to Healthy Ageing: What Has Indonesia Achieved So Far?

et al. 2021

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The World Health Organization (WHO) has projected that the world should prepare for an aging society. As the fourth most populous country in the world, the elderly population in Indonesia is also continuously growing. In 2010, the proportion of the elderly group was merely 5%, and it is expected to increase to 11% in 2035. Understanding the current situation of the adult population in Indonesia would be crucial to prepare for the future aging population. This article analyzed the current socio-demographic status, nutrition status, nutrient intake, and health profile of the current Indonesian adult population through a literature review. The key issues to prepare for healthy aging in Indonesia are summarized. Acknowledging the profile of the adult and senior adult population in Indonesia will provide beneficial information for all stakeholders in preparing Indonesia for a better healthy aging population with improved quality of life.

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“…24 Tulang secara terus menerus akan mengalami remodeling, yaitu keseimbangan dinamik antara resorpsi tulang oleh osteoklas dan pembentukan tulang oleh osteoblas. Faktor yang mempengaruhi remodeling tulang dan berdampak pada densitas tulang salah satunya adalah homeostasis mineral tulang, termasuk pengaturan kadar kalsium dalam darah yang melibatkan asupan kalsium, hormon paratiroid (PTH), dan vitamin D. 25 Nilai rerata densitas tulang mandibula anak tikus yang induknya diberi seduhan kopi Arabika dosis normal maupun berlebih menunjukkan adanya penurunan dibandingkan kelompok kontrol. Penelitian Lacerda, et al 11 juga menunjukkan hasil yang mirip dengan penelitian ini, membandingkan antara tikus yang diberi dan tanpa diberi kopi.…”

Section: Pembahasanunclassified

<p>Efek konsumsi kopi arabika berlebih selama masa laktasi terhadap densitas tulang mandibula anak tikus Wistar</p><p>The effect of excessive Arabica coffee consumption during lactation on the mandibular bone density of Wistar rats offspring</p>

2020

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Pendahuluan: Laktasi merupakan periode penting dalam pertumbuhan dan perkembangan bayi. Salah satu faktor risiko yang menyebabkan penurunan densitas tulang mandibula adalah konsumsi kopi berlebih selama masa laktasi. Penelitian ini bertujuan untuk menganalisis pengaruh konsumsi kopi Arabika selama masa laktasi terhadap densitas tulang mandibula anak tikus Wistar. Metode: Penelitian eksperimental laboratoris dilakukan terhadap 12 ekor tikus Wistar betina yang sedang menyusui. Penghitungan besar sampel berdasarkan jumlah kelompok penelitian (tiga kelompok), yaitu dengan rumus Arifin, dan didapatkan hasil empat ekor tikus untuk setiap kelompok penelitian, sehingga total jumlah sampel adalah 12 ekor tikus. Tiga kelompok penelitian terdiri dari kelompok kontrol (K) yang diberi akuades, kelompok perlakuan yang diberi kopi dosis normal (P1), dan kelompok perlakuan yang diberi kopi dosis berlebih (P2). Akuades dan kopi diberikan selama 21 hari sejak tikus mulai menyusui anaknya. Masing-masing induk tikus diambil satu anaknya untuk di-euthanasia pada hari ke-22. Kemudian dilakukan pengambilan sampel tulang mandibula dan dilakukan pengambilan rontgen foto periapikal. Selanjutnya dilakukan pengukuran densitas tulang mandibula menggunakan densitometer. Data dianalisis menggunakan uji one-way ANOVA dan LSD. Hasil: Hasil dari uji one-way ANOVA dari densitas tulang mandibula anak tikus menunjukkan bahwa terdapat perbedaan signifikan (p=0,0001) diantara seluruh kelompok penelitian. Hasil uji LSD menunjukkan perbedaan yang signifikan (p=0,0001) antara kelompok kontrol dengan kelompok yang diberi kopi dosis normal maupun dengan kelompok kopi dosis berlebih, demikian juga antara kelompok yang diberi dosis normal dengan dosis berlebih. Simpulan: Konsumsi kopi Arabika dalam dosis berlebih selama masa laktasi pada tikus Wistar dapat menurunkan densitas tulang mandibula anak tikus Wistar. Kata kunci: Laktasi, kopi arabika, densitas tulang mandibula. ABSTRACTIntroduction: Lactation is an important period in the growth and development. One of the risk factors that cause a decrease in mandibular bone density is excessive coffee consumption during lactation. This study was aimed to analyse the effect of coffee consumption, especially Arabica coffee, during lactation period on the rats’ mandibular bone density. Methods: This study was an experimental laboratory study of 12 lactating female Wistar rats. The sample size calculation was based on the number of research groups (three groups), the Arifin formula, and the results were four rats for each research group, so the total number of samples was 12 rats. The three research groups consisted of control group (K) which was given aquadest, treatment group that was given a normal dose of coffee (P1), and a treatment group that was given an excessive dose of coffee (P2). Aquadest and coffee were given for 21 days since the initial lactation period. One offspring of each female rat was taken to be euthanised on the 22nd day. Afterwards, the mandibular bone samples were taken from the young rats, and then the periapical x-rays was performed. Furthermore, the mandibular bone density measurement was carried out using a densitometer. Data was analysed using the one-way ANOVA and LSD tests. Results: The one-way ANOVA test of the mandibular bone density of the rats’ offspring showed a significant difference (p = 0.0001) between all study groups. The LSD test results showed a significant difference (p = 0.0001) between the control group and the group was given the normal dose of coffee and the group with an excessive dose of coffee and between the group that was given the normal and the excessive dose. Conclusion: Consumption of Arabica coffee in excessive dose during lactation of female Wistar rats can reduce the mandibular bone density of the offspring.Keywords: Lactation, arabica coffee, mandibular bone density.

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Peningkatan asupan kalsium menghambat penurunan kepadatan tulang pada perempuan pascamenopause

Cited by 5 publications

References 8 publications

Hubungan Asupan Kalsium dan Indeks Massa Tubuh dengan Kepadatan Tulang pada Wanita Usia Subur

Hubungan Asupan Kalsium dan Indeks Massa Tubuh dengan Kepadatan Tulang pada Wanita Usia Subur

The Road to Healthy Ageing: What Has Indonesia Achieved So Far?

<p>Efek konsumsi kopi arabika berlebih selama masa laktasi terhadap densitas tulang mandibula anak tikus Wistar</p><p>The effect of excessive Arabica coffee consumption during lactation on the mandibular bone density of Wistar rats offspring</p>

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