This paper aims to analyze the influence of systemic racism on quarter-life crisis, experienced by Malcolm X, as seen in The Autobiography of Malcolm X (As Told to Alex Haley). Its emphasis is to find the relation between racial segregation in American society and its influence on quarter-life crisis, which is a psychological crisis of uncertainty, self-insecurity and identity confusion, occurs during emerging adulthood. Therefore, by applying a qualitative method, this research is under Post-Nationalist American Studies and psychosocial approach as an integrated paradigm which accommodates the inter-disciplinary aspects of �self and society�. The analysis showed that racial segregation, in the field of education and job occupation, is a form of systemic racism which influences Malcolm X�s mental wellness as an emerging adult African-American. He experiences Robinson�s phases of quarter-life crisis which are locked in, separation/time-out, exploration and rebuilding. In fact, racial segregation in this narrative works as �a function of blocked opportunities� which disallows young African-Americans to develop their own competencies and to achieve their �American Dream�. However, in the development of his quarter-life crisis, Malcolm X managed to rebuild his new long-term commitment contributing to the reconstruction of his adult identity as an African-American Muslim activist.