Percutaneous coronary intervention triggers a systemic inflammatory response in patients treated for in-stent restenosis – comparison with stable and unstable angina

Koziński, Marek; Krzewina-Kowalska, Anna; Kubica, Jacek; Żbikowska-Gotz, Magdalena; Dymek, Grazyna; Piasecki, Radosław; Sukiennik, Adam; Grześk, Grzegorz; Bogdan, Maria; Chojnicki, Maciej; Dziedziczko, A; Sypniewska, Grażyna

doi:10.1007/s00011-005-1342-0

Cited by 25 publications

(12 citation statements)

References 39 publications

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“…An inflammatory response has been observed immediately following other cardiovascular procedures such as percutaneous coronary intervention [20], diagnostic coronary angiography [21], and cardiac surgery [22,23,24]. SIRS has also been observed following TAVI [10].…”

Section: Discussionmentioning

confidence: 99%

The Frequency and Prognostic Impact of Fever Following Transcatheter Aortic Valve Implantation

Orvin

Kornowski²,

Bishara³

et al. 2014

Cardiology

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Objectives: This study soughtto explore the frequency and prognostic implications of infectious and noninfectious fever following transcatheter aortic valve implantation (TAVI). Methods: We performed a retrospective cohort study including 194 consecutive patients who underwent TAVI at our institution. We identified and characterized all patients who developed fever within the first 72 h following the procedure. We determined the etiology of the fevers (infectious vs. noninfectious) and assessed their impact on in-hospital complications and 1-year mortality. Results: Following TAVI,65 (33.5%) patients had fever (mean age 83.7 ± 3.8 years, 70.2% female). An infectious etiology was evident in only 17 of the 65 patients (26.1%) with fever, mainly due to pneumonia (52.9%) and a urinary tract infection (41.2%). No significant difference was observed in baseline characteristics, the mean fever temperature/duration, or signs of inflammatory response between infectious and noninfectious fevers. The mean hospital duration was longer (7 ± 4.8 days vs. 4.7 ± 2.4 days, p = 0.01) among patients with an infectious fever; however, fever had no impact on the 1-year mortality rate (5.9 and 4.5%, respectively, p = 0.71). Conclusions: Our study demonstrates that, although fever was a common phenomenon after TAVI, it represented an infectious complication only in a minority of cases. Nevertheless, fever, infectious or not, had no impact on the 1-year mortality rate following TAVI.

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Section: Discussionmentioning

confidence: 99%

The Frequency and Prognostic Impact of Fever Following Transcatheter Aortic Valve Implantation

Orvin

Kornowski²,

Bishara³

et al. 2014

Cardiology

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“…Kozinski et al [45] did not find any significant difference in IL-10 concentrations in patients treated with PCI, whereas DominguezRodriguez et al [44] found that IL-10 levels are increased in patients with AMI treated with primary percutaneous transluminal coronary angioplasty. It has been, however, demonstrated that both systemic [9] and coronary atherosclerosis are associated with increased plasma concentrations of some inflammatory cytokines [46].…”

Section: Discussionmentioning

confidence: 97%

Th2-dependent cytokine release in patients treated with coronary angioplasty

Brunetti

Pepe

Munno

et al. 2008

Coronary Artery Disease

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“…Systemic markers of inflammation are increased in patients with ACS and usually rise within 24 h to 48 h after PCI [49,50]. Cross-reactions of abciximab with integrins avb3 and Mac-1 are assumed to decrease the endothelial inflammatory reaction.…”

Section: Abciximabmentioning

confidence: 99%