Performance analysis of photonic crystal based biosensor for the detection of bio-molecules in urine and blood

Yashaswini, P. R.; Gayathri, H.N.; Panigrahi, Suvasini

doi:10.1016/j.matpr.2021.06.192

Cited by 21 publications

(8 citation statements)

References 10 publications

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“…Equations (1) to (14) show the consideration of Transfer Matrix Method and its associated approach towards obtaining transmission and reflection properties of the 1D photonic crystal sensor. In the proposed biosensor, light from a laser source interacts with a multi-layered structure, typically consisting of a substrate, a sensing layer (where bimolecular interactions occur), and other intermediate layers.…”

Section: Design and Working Principlementioning

confidence: 99%

“…In contrast, the second design was rooted in advanced techniques, leading to it possessing ultra-quality factors, reasonable sensitivity, and compactness in size (9.4 × 5.5 μm 2 ). Ramanujam et al [14][15][16][17] presented a refractive index sensor based on ring core periodic structure of photonic crystal (PhC), which can be particularly used for tuberculosis blood samples. Materials for layer were selected as layer A is TiO 2 and layer B is SiO 2 , with a silicon material used around the hollow cavity to avoid changes in physical and chemical properties of real samples.…”

Section: Introductionmentioning

confidence: 99%

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Optofluidic photonic crystal micro sensor for enhanced detection of infectious diseases

Sharan,

Khouqeer,

El-Badry

et al. 2023

Eng. Res. Express

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This research encompasses a comprehensive study on the application of 1D photonic crystal-based detection in the context of infectious diseases, specifically targeting malaria stages, chikungunya, and dengue. It explores the interactions between the photonic crystal and various biomolecules associated with these diseases, with a focus on platelets, plasma, and uric acid. The transmission spectrum graphs obtained from these interactions provide crucial insights into the detection and quantification of the diseases, offering real-time and label-free monitoring capabilities. Maximum sensitivity of 550 nm RIU−1 and Q factor of 29,260 obtained. Additionally, the study incorporates the design and analysis of a microfluidic channel optimized for the proposed sensor, ensuring accurate temperature and pressure distributions. The results demonstrate the feasibility of the microfluidic platform for enhancing sensor performance and fluid handling. This integrated approach shows promising potential for early disease diagnosis and monitoring, paving the way for practical implementation and further advancements in the field of sensing and diagnostics

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Section: Design and Working Principlementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Optofluidic photonic crystal micro sensor for enhanced detection of infectious diseases

Sharan,

Khouqeer,

El-Badry

et al. 2023

Eng. Res. Express

View full text Add to dashboard Cite

show abstract

“…The growing demand for optical sensing applications has raised the significance of PhC-based optical technologies. Due to the PBG property and the light confinement capability of the PhC-based structures, PhCs and their applications in healthcare, 116 – 120 RI sensing, 121 – 124 quality control of food, 125 – 128 and in many other fields 129 – 132 is now the sphere of interest for researchers in the present era (Table 3).…”

Section: Applications Of Phcmentioning

confidence: 99%

Fabrication techniques and applications of two-dimensional photonic crystal: history and the present status

2022

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The idea of photonic crystal came to be when E. Yablonovitch and S. John recommended a structure in 1987 having periodic alteration of refractive index in one or multiple directions. Photonic crystals have the potential to manipulate and tailor the flow of light across the crystal, which gives advantage to invent many photonic devices on the microscopic scale having very small footprints. In recent years several articles have been published on the advances of photonic crystal-based structures. This review article mainly focuses on the several fabrication techniques of photonic crystals and their applications in different fields. Several photonic crystalbased structures such as logic gates, optical sensors, polarization beam splitters, and absorbers for solar cells are reviewed in this paper to show recent advancements on this trending topic. Also, a brief review of the different steps of fabrication of photonic crystals and different fabrication methods proposed by researchers is articulated in this paper.

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“…PC-based glucose monitoring has been widely investigated in the infrared regime. [28][29][30] In this paper, a biosensor based on a new 1D ternary PC (TPC) structure based on Si, Nb 2 O 5 , and SiO 2 with a defect layer is proposed for monitoring glucose in urine, which has not previously been done to our knowledge. It is easier and more available than blood testing.…”

Section: Introductionmentioning

confidence: 99%

“…Surface plasmon resonance, 25 2D-PC structure, 16 long-period fiber grating, 26 and different types of ring resonators 27 are examples of optical RI instruments. PC-based glucose monitoring has been widely investigated in the infrared regime 28 – 30 …”

Section: Introductionmentioning

confidence: 99%

One-dimensional photonic crystal-based biosensor for the detection of glucose concentration in human urine

et al. 2023

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A biosensor structure based on a ternary photonic crystal (TPC) containing a defect is designed and simulated. This proposed biosensor detects the concentration of glucose in human urine. Based on the transfer matrix method, we theoretically studied the transmission spectra through the TPC presuming blood samples with different refractive indices (RIs) infiltrated into the defect layer of the proposed structures. By varying the concentration of glucose in the urine, the RI of the urine is changed, which in turn changes the sensor's output response; both transmission response and resonance wavelength are affected. We evaluated average sensitivity (S) for the number of periods at different values N for optimization purposes. Our results show that the biosensor has performance parameters for a period value N ¼ 6. Indeed, a value of 1033 nm of full width at half maximum photonic bandgap can be observed with a S of 965 nm∕RIU. The quality factor is 1892.542 and the figure of merit is 756.86 RIU −1 . The proposed biosensor can be a miniaturized structure with extreme sensitivity in the concentration of glucose detection models © 2023 Society of Photo-Optical Instrumentation Engineers (SPIE)

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Performance analysis of photonic crystal based biosensor for the detection of bio-molecules in urine and blood

Cited by 21 publications

References 10 publications

Optofluidic photonic crystal micro sensor for enhanced detection of infectious diseases

Optofluidic photonic crystal micro sensor for enhanced detection of infectious diseases

Fabrication techniques and applications of two-dimensional photonic crystal: history and the present status

One-dimensional photonic crystal-based biosensor for the detection of glucose concentration in human urine

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