Periostitis, Aseptic Necrosis, and Arthritis Occurring in a Patient with Crohn's Disease

Brom, B; Bank, Simmy; Marks, I. N.; Cobb, Joseph

doi:10.1016/s0016-5085(71)80038-0

Cited by 30 publications

(13 citation statements)

References 16 publications

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“…This may result in clubbing of the fingers or toes, and may be associated with articular cartilage erosion and synovial membrane hypertrophy. Periostitis has also been described around the knee joints in association with avascular necrosis of the humeral heads (44). The association with corticosteroid use is unclear.…”

Section: Hypertrophic Osteoarthropathymentioning

confidence: 99%

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Bones and Crohn's: Problems and solutions

Buchman

2007

Inflamm Bowel Dis

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Inflammatory bowel disease may manifest in various extra intestinal manifestations. Osteopenia and various arthropathies may be debilitating. These may be related to the disease itself, patient genetics, lifestyle, or disease treatment. Calcium and vitamin D malabsorption, vitamin K deficiency, malnutrition, corticosteroid and other immunosuppressive medications, smoking, lack of exercise and postmenopausal state may all play important roles. Treatment may be undertaken to correct nutrient deficiencies, inhibit bone resorption and increase bone formation.

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Section: Hypertrophic Osteoarthropathymentioning

confidence: 99%

“…Aseptic necrosis of the femoral head has most often been described as a complication of long-term corticosteroid use (44,(47)(48)(49)(50). Typically this process occurs within 4-6 months of corticosteroid initiation.…”

Section: Aseptic Necrosismentioning

confidence: 99%

Bones and Crohn's: Problems and solutions

Buchman

2007

Inflamm Bowel Dis

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“…In published series of arthritis of peripheral joints in patients with Crohn's disease the symptoms have been confined mainly to the knees and ankles and sometimes to the finger joints with subacute mi-grating asymmetrical polyarthritis (Ansell and Wigley, 1964;Wagner, 1969;Thayer, 1970;Brom, Bank, Marks, and Cobb, 1971).…”

Section: Discussionmentioning

confidence: 99%

Granulomatous arthritis in Crohn's disease

Lindström¹,

Wramsby²,

Ostberg³

1972

Gut

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“…Dennoch gelten der Morbus Crohn und die Colitis ulcerosa als Risikofaktor für aseptische Knochennekrosen. Sie werden in Verbindung mit einer Steroidtherapie, aber auch ohne eine solche beschrieben (1)(2)(3)(4)(5)(6)(7)(9)(10)(11)(12)(13)(14). Bis heute ist unklar, ob aseptische Knochennekrosen nicht eine seltene extraintestinale Manifestation der chronisch entzündlichen Darmerkrankung sind.…”

Section: Rezidivierende Aseptische Knochennekrosen Beiunclassified

“…In 80% kommt es zu beidseitigem Befall. Multifokale Lä-sionen in den Extremitätenknochen sind häufig (2,10,12,13 …”

Section: Diskussionunclassified