Pesticide multi-residues in Dendrobium officinale Kimura et Migo: Method validation, residue levels and dietary exposure risk assessment

Xu, Zhihong; Li, Lingxiangyu; Xu, Yi; Wang, Shanshan; Zhang, Xiaoxia; Tang, Tao; Yu, Jianzhong; Zhao, Huiyu; Wu, Shenggan; Zhang, Chunrong; Zhao, Xiujuan

doi:10.1016/j.foodchem.2020.128490

Cited by 58 publications

(24 citation statements)

References 19 publications

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“…In particular, Wu and Feng (2019) revealed that the content of polysaccharides is the highest in those samples collected from October to the following March (Wu and Feng, 2019). Yu et al (2014) found that it is more reasonable to harvest D. officinale at biennials pre-bloom than at specific harvesting months according to the content of polysaccharides (Xu et al, 2021). According to the Editorial Board of Chinese Pharmacopoeia (2020) edition, however, D. officinale should be harvested from November to the following March (China Pharmacopoeia Committee, 2020).…”

Section: Quality Controlmentioning

confidence: 99%

Traditional Uses, Phytochemistry, Pharmacology, and Quality Control of Dendrobium officinale Kimura et. Migo

Wen-hua

Zhang

et al. 2021

Front. Pharmacol.

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Dendrobium officinale, a well-known plant used as a medicinal and food homologous product, has been reported to contain various bioactive components, such as polysaccharides, bibenzyls, phenanthrenes, and flavonoids. It is also widely used as a traditional medicine to strengthen “Yin”, nourish heart, tonify five viscera, remove arthralgia, relieve fatigue, thicken stomach, lighten body, and prolong life span. These traditional applications are in consistent with modern pharmacological studies, which have demonstrated that D. officinale exhibits various biological functions, such as cardioprotective, anti-tumor, gastrointestinal protective, anti-diabetes, immunomodulatory, anti-aging, and anti-osteoporosis effects. In this review, we summarize the research progress of D. officinale from November 2016 to May 2021 and aim to better understand the botany, traditional use, phytochemistry, and pharmacology of D. officinale, as well as its quality control and safety. This work presents the development status of D. officinale, analyzes gaps in the current research on D. officinale, and raises the corresponding solutions to provide references and potential directions for further studies of D. officinale.

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Section: Quality Controlmentioning

confidence: 99%

Traditional Uses, Phytochemistry, Pharmacology, and Quality Control of Dendrobium officinale Kimura et. Migo

Wen-hua

Zhang

et al. 2021

Front. Pharmacol.

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“…Among the most prevalent solvents, MeCN has been commonly utilized in the QuEChERS extraction protocol since it can limit the influences of non-polar compounds such as fats, waxes, and pigments present in the sample matrix compared to other solvents [11]. Moreover, previous studies pointed out that the use of acetic acid considerably improves the extraction efficiency of the target analytes even at trace levels [12]. Moreover, the addition of acetic acid to MeCN exhibits the stability enhancement of several unstable pesticides [13].…”

Section: Selection Of Extraction Solventmentioning

confidence: 99%

A Combination of Chromatography with Tandem Mass Spectrometry Systems (UPLC-MS/MS and GC-MS/MS), Modified QuEChERS Extraction and Mixed-Mode SPE Clean-Up Method for the Analysis of 656 Pesticide Residues in Rice

Tran-Lam

Bui

Nguyen

et al. 2021

Foods

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The emerging ungovernable application of pesticides in rice farming has attracted public concerns as these hazardous chemicals leave long-lasting environmental impacts and cause severe health effects. Here, an optimized analytical method was proposed for the measurement of 656 pesticide residues in rice samples collected in Vietnam. We utilized chromatography with tandem mass spectrometry systems (UPLC-MS/MS and GC-MS/MS) combined with a modified quick, easy, cheap, effective, rugged, and safe (QuEChERS) extraction method and adopted a mixed-mode SPE clean-up method for the analysis. The results showed that a total of 341 and 315 compounds were determined by UPLC- and GC-MS/MS, respectively. Usage of 10 mL MeCN, 5 mL H2O and 1% glacial acetic acid as extraction solvent outperformed other mixtures in purifying the analytes from the sample matrix. Besides, pressure swing adsorption connected to a C18 cartridge with C18 placed on top exhibited remarkably more extracted compounds of high recovery which resulted in 299 and 318 compounds with recovery ranging from 70 to 120% in GC- and UPLC-MS/MS, respectively. Our optimized protocols also resulted in maximal limits of quantification of 10 μg Kg−1 in both MS methods with repeatability and reproducibility less than 20%. Application of validated method on 20 rice samples collected in Hanoi, Vietnam showed that 14 samples were contaminated with at least one pesticide, and insecticide was the most detected group. Overall, the compliance of all method validation parameters to SANTE/12682/2019 Guideline demonstrates that this protocol can be employed for the effective management of Vietnam’s rice in accordance with international requirements.

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“…[3][4][5] For example, Dendrobium officinale (DO) is listed in the Pharmacopoeia of the People's Republic of China, where polysaccharide is considered as its functional ingredients. 6,7 However, the quality of polysaccharides and related products can vary significantly from plants of different origins, regions of planting, processing methods, etc. 8,9 There are no generally accepted methods to rapidly characterize polysaccharide components.…”

Section: Introductionmentioning

confidence: 99%

Rapid fingerprint analysis for herbal polysaccharides using direct analysis in real‐time ionization mass spectrometry

Wang

Jiang

Liu

et al. 2021

Rapid Comm Mass Spectrometry

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Herbal polysaccharides have various potential medicinal values.Development of reliable analytical method for the fingerprint analysis of polysaccharides is critical for their quality assessment, origin identification, and authenticity evaluation.Methods: Mechanochemical extraction (MCE) was used to extract polysaccharide components from different herbal species. Intact polysaccharides were then directly analyzed by direct analysis in real-time mass spectrometry (DART-MS). Standard addition method with isotope-labeled internal standard was used to quantify polysaccharide amounts directly from liquid extract. Multivariate data analysis was further conducted for species classification.Results: The intact and large polysaccharides were decomposed into small fragment ions less than m/z 350 instantaneously using DART ion source. Different polysaccharides showed distinguished fingerprint DART-MS spectra using both individual and mixed herbal species. The liquid supernatant from MCE was validated to be used as direct sample for DART-MS analysis. Quantitation was successfully achieved for polysaccharide contents in Dendrobium officinale from different locations.Conclusions: A rapid fingerprint protocol in combination of MCE and DART-MS for herbal polysaccharides was developed. The whole process could be accomplished within a few minutes, from raw materials to final spectra, without requirements of pre-digestion and additional sample purification.

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Pesticide multi-residues in Dendrobium officinale Kimura et Migo: Method validation, residue levels and dietary exposure risk assessment

Cited by 58 publications

References 19 publications

Traditional Uses, Phytochemistry, Pharmacology, and Quality Control of Dendrobium officinale Kimura et. Migo

Traditional Uses, Phytochemistry, Pharmacology, and Quality Control of Dendrobium officinale Kimura et. Migo

A Combination of Chromatography with Tandem Mass Spectrometry Systems (UPLC-MS/MS and GC-MS/MS), Modified QuEChERS Extraction and Mixed-Mode SPE Clean-Up Method for the Analysis of 656 Pesticide Residues in Rice

Rapid fingerprint analysis for herbal polysaccharides using direct analysis in real‐time ionization mass spectrometry

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