Phenolic Contents, Antioxidant, and Antibacterial Activities of the Algerian <i>Genista saharae</i> Solvent Extracts

Barek, Said; Rahmoun, Nadjib Mohammed; Aissaoui, Mohammed; Haci, Imad Abdelhamid El; Bensouici, Chawki; Choukchou‐Braham, Noureddine

doi:10.1080/10496475.2019.1661327

Cited by 10 publications

(10 citation statements)

References 31 publications

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“…The products with the electron-withdrawing groups in position 4 showed antibacterial activity with respect to gram-positive and -negative bacteria. These results are in accordance with the work of Nirav et al, 30 which focused on the synthesis and evaluation of the antimicrobial activity of a new series of 4H-chromenes against Staphylococcus aureus (S. aureus), and Bacillus subtilis (B. subtilis). The best result has been observed with chromene, which has a chlorine group.…”

Section: Total Antioxidant Capacity (Tac)supporting

confidence: 92%

Synthesis and Biological Evaluation of New Chromenes and Chromeno[2,3-d] pyrimidines

et al. 2021

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A simple and efficient approach has been developed to synthesise novel and functionalised 5H-chromeno[2,3-d] pyrimidines derivatives (4a-h). This approach entails treating 2-amino-3-cyano-4H-chromenes (3a-h) with formamidine acetate under microwave irradiations and solvent-free conditions. All structures of new compounds obtained in this study were characterised by IR, MS, 1H and 13C NMR analysis. Additionally, the synthesised compounds were investigated for their antibacterial and antioxidant potential. Compounds 3b, 3c, 3e, 4c and 4e showed significant activities. Keywords: 5H-chromeno[2,3-d] pyrimidine; 4H-chromene; solvent-free conditions; antioxidant activity; antibacterial activity

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Section: Total Antioxidant Capacity (Tac)supporting

confidence: 92%

Synthesis and Biological Evaluation of New Chromenes and Chromeno[2,3-d] pyrimidines

et al. 2021

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“…Furthermore, phenolic and flavonoid constituents in plants are responsible for the antioxidant activities in MPs (Barek et al, 2020), which increased in biochar treatments. Also, the correlation of pharmacologically active compounds and antioxidants activities with the nutrient of plants is consistent with these findings.…”

Section: Discussionmentioning

confidence: 99%

Biochar amendment reduced the risk associated with metal uptake and improved metabolite content in medicinal herbs

Nigam

Khare

Ahsan

et al. 2021

Physiologia Plantarum

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Contaminations of heavy metals such as lead (Pb) and cadmium (Cd) in medicinal plants (MPs) not only restrict their safe consumption due to health hazards but also lower their productivity. Biochar amendments in the soil are supposed to immobilize the toxic metals, improve the soil quality, and agricultural productivity. However, the impact of biochar on growth attributes, metal accumulation, pharmacologically active compounds of MPs, and health risk is less explored. An experiment was performed on three medicinal plants [Bacopa monnieri (L.), Andrographis paniculata (Burmf.) Nees, and Withania somnifera (L.)] grown in a greenhouse in soil co‐contaminated with Pb and Cd (at two concentrations) without and with biochar amendments (2% and 4% application rates). The fractionation of Pb and Cd, plant growth parameters, stress enzymes, photosynthetic capacity, pharmacologically active compounds, nutrient content, uptake and translocation of metals, antioxidant activities, and metabolite content were examined in the three MPs. The accumulation of Pb and Cd varied from 3.25–228 and 1.29–20.2 mg kg−1, respectively, in the three MPs, while it was reduced to 0.08–18 and 0.03–6.05 mg kg−1upon biochar treatments. Plants grown in Pb and Cd co‐contaminated soil had reduced plant biomass (5%–50% depending on the species) compared to control and a deleterious effect on photosynthetic attributes and protein content. However, biochar amendments significantly improved plant biomass (21%–175%), as well as photosynthesis attributes, chlorophyll, and protein contents. Biochar amendments in Pb and Cd co‐contaminated soil significantly reduced the health hazard quotient (HQ) estimated for the consumption of these medicinal herbs grown on metal‐rich soil. An enhancement in secondary metabolite content and antioxidant properties was also observed upon biochar treatments. These multiple beneficial effects of biochar supplementation in Pb and Cd co‐contaminated soil suggested that a biochar amendment is a sustainable approach for the safe cultivation of MPs.

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“…The chloroform extract, containing high amounts of quercetin and naringenin, revealed the antioxidant potential and antibacterial activity against the bacterial strains (MIC 0.02 mg/mL). These results seemed to indicate a high contribution of quercetin and naringenin in the antimicrobial and antioxidant activities recorded [ 39 ].…”

Section: Natural Extracts With Antimicrobial Activitymentioning

confidence: 99%

Nanotechnologies: An Innovative Tool to Release Natural Extracts with Antimicrobial Properties

et al. 2021

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Site-Specific release of active molecules with antimicrobial activity spurred the interest in the development of innovative polymeric nanocarriers. In the preparation of polymeric devices, nanotechnologies usually overcome the inconvenience frequently related to other synthetic strategies. High performing nanocarriers were synthesized using a wide range of starting polymer structures, with tailored features and great chemical versatility. Over the last decade, many antimicrobial substances originating from plants, herbs, and agro-food waste by-products were deeply investigated, significantly catching the interest of the scientific community. In this review, the most innovative strategies to synthesize nanodevices able to release antimicrobial natural extracts were discussed. In this regard, the properties and structure of the starting polymers, either synthetic or natural, as well as the antimicrobial activity of the biomolecules were deeply investigated, outlining the right combination able to inhibit pathogens in specific biological compartments.

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Phenolic Contents, Antioxidant, and Antibacterial Activities of the Algerian Genista saharae Solvent Extracts

Cited by 10 publications

References 31 publications

Synthesis and Biological Evaluation of New Chromenes and Chromeno[2,3-d] pyrimidines

Synthesis and Biological Evaluation of New Chromenes and Chromeno[2,3-d] pyrimidines

Biochar amendment reduced the risk associated with metal uptake and improved metabolite content in medicinal herbs

Nanotechnologies: An Innovative Tool to Release Natural Extracts with Antimicrobial Properties

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