PO-0726 International Survey On Peri-extubation Practices In Extremely Premature Infants

Mandhari, Hilal Al; Shalish, Wissam; Dempsey, Eugene M.; Keszler, Martin; Davis, Peter G

doi:10.1136/archdischild-2014-307384.1366

Cited by 4 publications

(4 citation statements)

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“…However, there is no consensus on a standardised weaning protocol [13], even though they can be of benefit [14]. In practice protocols can vary between institutions, and may include different parameters [15]. This is mainly due to uncertainty, so an automated prediction model to indicate when extubation may be appropriate is likely to be helpful to clinicians seeking to make better-informed decisions.…”

Section: Introductionmentioning

confidence: 99%

Prediction of weaning from mechanical ventilation using Convolutional Neural Networks

Jia

Kaul

Lawton

et al. 2021

Artificial Intelligence in Medicine

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Section: Introductionmentioning

confidence: 99%

Prediction of weaning from mechanical ventilation using Convolutional Neural Networks

Jia

Kaul

Lawton

et al. 2021

Artificial Intelligence in Medicine

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“…Despite advances in technology, the extubation decision making is still a complex and difficult task for clinicians [12]. Actually, there is no consensus on a standardized or objective weaning protocol [13], and it is controversial which parameters should be included in that protocol, even though the use of weaning protocols sometimes could be helpful [14]. Further, the actual applying of weaning protocol varies individually and even varies amongst different insititutions [13].…”

Section: Introductionmentioning

confidence: 99%

“…Actually, there is no consensus on a standardized or objective weaning protocol [13], and it is controversial which parameters should be included in that protocol, even though the use of weaning protocols sometimes could be helpful [14]. Further, the actual applying of weaning protocol varies individually and even varies amongst different insititutions [13]. To help clinicians make more informed decision, an automated prediction tool for extubation is necessary.…”

Section: Introductionmentioning

confidence: 99%

Prediction of Extubation Failure for Intensive Care Unit Patients Using Light Gradient Boosting Machine

Chen

Ying

et al. 2019

IEEE Access

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Extubation failure is a complex and ongoing problem in the intensive care unit (ICU). It refers to the patients who require re-intubation after extubation (namely disconnection from mechanical ventilation). In these patients, extubation failure leads to severe risks associated with re-intubation and is associated with increased mortalities, longer stay in ICU and also higher health care costs. Many studies have been proposed to analyze the problem of extubation failure and identify possible factors or indices that may predict extubation failure. However, these studies used a small number of patients for extubation failure and limited their features to several vital signs or main characteristics. We argue that these are insufficient and less accurate for the prediction of extubation failure. In this paper, we analyze 3636 adult patient records in the MIMIC-III clinical database and apply the Light Gradient Boosting Machine (LightGBM) to predict extubation failure. Also, we perform feature importance analysis according to the result of LightGBM and interpret these features using SHapley Additive exPlanations (SHAP). Experimental results show that our LightGBM method is effective in predicting extubation failure and outperform other machine learning methods such as artificial neural network (ANN), logistic regression (LR) and support vector machine (SVM). The results of feature importance and SHAP analysis are also proved effective and accurate.

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“…To assess extubation readiness, clinicians routinely use blood gas results, ventilator settings, and clinical expertise. However, there is no consensus on an objective weaning protocol, and practice varies individually and amongst institutions [5]. Indeed, studies have reported wide ranges of reintubation rates depending on several factors including the time frame used to define extubation failure [4,6].…”

Section: Introductionmentioning

confidence: 99%

Undersampling and Bagging of Decision Trees in the Analysis of Cardiorespiratory Behavior for the Prediction of Extubation Readiness in Extremely Preterm Infants

Kanbar¹,

Onu²,

Shalish³

et al. 2018

2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

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Extremely preterm infants often require endotracheal intubation and mechanical ventilation during the first days of life. Due to the detrimental effects of prolonged invasive mechanical ventilation (IMV), clinicians aim to extubate infants as soon as they deem them ready. Unfortunately, existing strategies for prediction of extubation readiness vary across clinicians and institutions, and lead to high reintubation rates. We present an approach using Random Forest classifiers for the analysis of cardiorespiratory variability to predict extubation readiness. We address the issue of data imbalance by employing random undersampling of examples from the majority class before training each Decision Tree in a bag. By incorporating clinical domain knowledge, we further demonstrate that our classifier could have identified 71% of infants who failed extubation, while maintaining a success detection rate of 78%.  Pause (PAU): cessation of breathing indicated by low RCG and ABD power in the breathing band (0.4-2Hz).  Movement Artifact (MVT): periods during which there is power in the movement artifact band (0-0.4Hz) due to infant movement or nurse handling.  Synchronous Breathing (SYB): periods during which RCG and ABD are in synchrony.  Asynchronous Breathing (ASB): periods during which RCG and ABD are out of synchrony.AUREA is objective, repeatable, and has been tuned for this population. Further details are given in [13]. The following patterns were also extracted from the ECG and PPG signals: Bradycardia (BDY): artifact-free periods during which and the heart rate was below 100 beats/min.

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PO-0726 International Survey On Peri-extubation Practices In Extremely Premature Infants

Cited by 4 publications

References 0 publications

Prediction of weaning from mechanical ventilation using Convolutional Neural Networks

Prediction of weaning from mechanical ventilation using Convolutional Neural Networks

Prediction of Extubation Failure for Intensive Care Unit Patients Using Light Gradient Boosting Machine

Undersampling and Bagging of Decision Trees in the Analysis of Cardiorespiratory Behavior for the Prediction of Extubation Readiness in Extremely Preterm Infants

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