2021
DOI: 10.1021/acs.nanolett.0c04942
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Point-of-Care Pathogen Testing Using Photonic Crystals and Machine Vision for Diagnosis of Urinary Tract Infections

Abstract: Urinary tract infections (UTIs) caused by bacterial invasion can lead to life-threatening complications, posing a significant health threat to more than 150 million people worldwide. As a result, there is need for accurate and rapid diagnosis of UTIs to enable more effective treatment. Described here is an intelligent diagnostic system constructed for bacterial detection using an immunobiosensor, signal-amplification biochip, and image processing algorithm based on machine vision. This prototype can quickly de… Show more

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Cited by 53 publications
(37 citation statements)
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“…In the process of coordinate calibration, machine vision model is mainly analyzed from two aspects: coordinate transformation and corresponding coordinate optimization [12,13].…”
Section: Machine Vision Model Calibrationmentioning
confidence: 99%
“…In the process of coordinate calibration, machine vision model is mainly analyzed from two aspects: coordinate transformation and corresponding coordinate optimization [12,13].…”
Section: Machine Vision Model Calibrationmentioning
confidence: 99%
“…Yet, the reliance on manual observation rather than instrumental measurement might cause large subjective uncertainty, as well as difficulty in quantitative data. The integration of digital technology [126] (e.g., machine vision) to simulate human visual ability and objective perception, the accurate and reliable results could be easily quantified, and thus reducing subjective errors in manual observations.…”
Section: Discussionmentioning
confidence: 99%
“…In the presence of P. aeruginosa , red-shifts reflection spectra occurred due to the expansion of hydrogel, which in turn increases the lattice spacing [ 146 ]. Liu and co-workers explored the photonic crystal-based biochips to detect bacteria in urine samples with the help of a machine vision (MV) diagnostic system [ 161 ]. The MV algorithm gives precise results, and apparently is a promising technology for developing POC applications.…”
Section: Biosensors For Pathogen Detectionmentioning
confidence: 99%
“…A brief summary of the emerging smart materials for microbial pathogens is shown in Table 3. Not mentioned [160] Not mentioned [146] Not mentioned [161] strategies of E. coli using the nanoarray setup. Reprinted with permission from Ref.…”
Section: Responsive Polymer Based Systemmentioning
confidence: 99%