Porous microspheres based on hydroxyapatite-graft-poly (γ-benzyl-l-glutamate) with improving homogeneity of hydroxyapatite and osteogenesis

Microcarriers with Controllable Size via Electrified Liquid Jets and Phase Separation Technique Promote Cell Proliferation and Osteogenic Differentiation

“…19 The amido bond of PBLG may mimic the natural ECM structure to provide a suitable surface for cells, and PBLG possesses a high calcium binding affinity, which could induce osteoblast differentiation, rapid mineralization, and new bone formation. 20 Yin et al 21 prepared hydroxyapatite-graf t-poly(γ-benzyl-L-glutamate) microcarriers, and they found that the rabbit-adipose-derived stem cells (r-ADSCs) seeded in HA-g-PBLG microspheres exhibited more uniform osteogenic differentiation and higher expression of osteogenic genes. Therefore, grafted PBLG molecules could bring good osteogenesis activity for HA and also enhance its interface compatibility with PLGA matrix.…”

Dendrimer-Au Nanoparticle Network Covered Alumina Membrane for Ion Rectification and Enhanced Bioanalysis

“…It is notable that the DAN/AAO hybrid exhibits singular signals at 101.4 eV ascribed to −Si−O− from the coupling reagent of APTES (Figure 1H) and two obvious Au 4f peaks at 82.5 and 86.5 eV, respectively, from AuNPs (Figure 1I). In addition, energy dispersive spectroscopy (EDS) mapping of the SEM images (Figure S2) was used to identify the elemental distribution of Au, Si, N, O, and C. 31 It can be seen that the Au and Si atoms are dispersed homogeneously in the architecture, indicating the formation of the DAN film on the top of AAO. These results demonstrate the successful formation of the DAN/AAO hybrid.…”