Potentials of <i>Melastoma malabathricum</i> Linn. Flower and Fruit Extracts as Antimicrobial Infusions

Abstract

<i>Melastoma malabathricum</i> Linn. is a shrub that belongs to the family <i>Melastomataceae</i> and a common herbal plant used in folk medicines to treat inflamed wounds. This study was carried out with the aim to evaluate the inhibitory activities of different concentrations of the <i>M. malabathricum</i> Linn. flower and fruit crude extracts against a variety of microorganisms. The inhibitory effects of both extracts were tested against the microorganisms using the disc diffusion method. The lowest concentrations of the extracts producing inhibition zones against the test microorganisms were used to determine their Minimum Inhibitory Concentrations (MICs) and Minimum Microbicidal Concentrations (MMCs). Both crude extracts showed strong inhibitory activities against Gram-positive bacteria. The range of MIC values for the crude flower and fruit extracts on all the bacteria tested were 12.5 to 100.0 mg/ml. Overall, Gram-positive bacteria were more susceptible to the crude extracts compared to Gram-negative species, potentiating a possible use of the extracts to inhibit or kill potential pathogens

Antioxidant, antibacterial activity and FICI (Fractional Inhibitory Concentration Index) of ethanolic extract of Melastoma malabathricum leaves with amoxicillin against pathogenic bacteria

“…MIC value of M. malabathricum leaf ethanol extract towards bacteria P. mirabilis is 1.56 mg/mL. This result is different from research conducted by Omar et al (2012), which stated that MIC value in Melastoma malabathricum L. flower extract is 50 mg/mL (Omar et al 2012). The different concentrations can be caused by the other part of plants used.…”

Masker All In 1 Buah Senduduk Kaya Antioksidan dan Antibakteri

“…(Farizah, et al, 2018). Selain itu, Omar, et al (2012) membuktikan pada penelitiannya menggunakan ekstrak bunga dan buah senduduk bahwa penggunaan ekstrak tersebut menghambat atau membunuh patogen potensial. Sejalan dengan itu Isnaini, Yasmina dan Nur'amin (2019) membuktikan adanya kandungan quercetin dan kaempferol yang memiliki antioksidan dan aktivitas antikanker pada ekstrak bunga buah senduduk.…”

Optical characterization and concentration-dependent antibacterial activity of silver nanoparticles (AgNPs) using aqueous Melastoma malabathricum extract against Staphylococcus aureus

“…This plant has been used because it is widely spread in Malaysia (Liu et al, 2014). M malabathricum, commonly called 'senduduk' is a plant that belongs to family Melastomataceae and a common herbal plant used in folk medicine (Omar et al, 2012). This plant had been used traditionally to treat toothache, diarrhoea, scar prevention and anti-infection from the extraction of root and lower crude (Balamurugan et al, 2014).…”