Precise determination of the dielectric constant and thickness of a nanolayer by use of surface plasmon resonance sensing and multiexperiment linear data analysis

Abstract

Surface plasmon resonance (SPR) sensing and an enhanced data analysis technique are used to obtain precise predictions of the dielectric constant and thickness of a nanolayer. In the proposed approach, a modified analytical method is used to obtain initial estimates of the dielectric constants and thicknesses of the metal film and a nanolayer on the sensing surface of a SPR sensor. A multiexperiment data analysis approach based on a two-solvent SPR method is then employed to improve the initial estimates by suppressing the noise in the measurement data. The proposed two-stage approach is employed to determine the dielectric constant and thickness of a molecular imprinting polymer nanolayer. It is found that the results are in good agreement with those obtained with an ellipsometer and a high-resolution scanning electron microscope.

Molecular imprinting science and technology: a survey of the literature for the years 2004-2011

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Surface Plasmon Resonance‐Based Fiber Optic Sensors: Principle, Probe Designs, and Some Applications

“…Change in refractive index changes the value of the resonance parameter. To excite surface plasmons, generally, a prism is used [2][3][4][5][6][7][8][9]. The prism-based SPR sensing device has a number of shortcomings such as its bulky size and the presence of various optical and mechanical (moving) parts.…”

Single-Molecule Blinking Fluorescence Enhancement by Surface Plasmon-Coupled Emission-Based Substrates for Single-Molecule Localization Imaging

“…The reflectivity profiles of the four silver layers at diverse incident angles were collected by tuning the incident angles with a motorized goniometer; the results are presented in Figure S1. After applying a fitting approach, the thicknesses of the four silver layers were estimated to be approximately 29, 37, 45, and 52 nm, respectively.…”

“…The reflectivity profiles of the four silver layers at diverse incident angles were collected by tuning the incident angles with a motorized goniometer; the results are presented in Figure S1. After applying a fitting approach, 34 The SPCE substrates were then soaked in 1 mM 2aminoethanethiol hydrochloride in ethanol solution for 6 h, rinsed three times with ethanol, and dried in a stream of nitrogen to form a self-assembled monolayer and to complete the surface functionalization of the silver layers. After performing silver-layer coating on the substrate surface, we immediately subjected SPCE substrates to the thiolate protection process to reduce the oxidation of the silver layer.…”