Preconditioning-like amelioration of erythropoietin against laparoscopy-induced oxidative injury

Abstract

Laparoscopic preconditioning is more effective than the preischemic administration of erythropoietin in reducing laparoscopy-induced oxidative injury.

N-acetylcysteine (NAC) Protects Against Acute Kidney Injury (AKI) Following Prolonged Pneumoperitoneum in the Rat

“…The administration of erythropoietin before the pneumoperitoneum significantly decreased the plasma levels of LDH, TNF-a, and MDA, compared with those found in the laparoscopy group [17].…”

Synergistic effect of erythropoietin but not G-CSF in combination with curcumin on impaired liver regeneration in rats

“…in the kidney [10], liver [11], brain [12] and heart [13]. Other injuries like laparoscopy-induced oxidative stress [14] or septic liver failure could also be attenuated by Epo prophylaxis or treatment [15].…”

Does prolonged pneumoperitoneum affect the kidney? Oxidative stress, stereological and electron microscopy study in a rat model

“…These experiments used intra-abdominal pressures routinely applied in human clinical settings (12 to 15 mmHg) (2)(3)(4)(5)(6). However, recent evidences indicate that Pp above 8 mmHg in rats correspond to much higher pressures than those that are normally used in humans.…”