Predicting complications following radical cystectomy with the ACS NSQIP universal surgical risk calculator

Mannas, Miles; Lee, TaeWeon; Forbes, Connor M.; Hong, Tracey; Bisaillon, Andrea; Gleave, Martin; So, Alan; Mayson, Kelly; Black, Peter C.

doi:10.1007/s00345-019-02915-3

Cited by 15 publications

(22 citation statements)

References 9 publications

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“…Pelvic exenteration surgery can be performed with low morbidity, as documented by grade 4 complications occurring in only 8.1% of patients in the present study, which is comparable to the peri-operative complication rates reported by others [16][17][18]. Also, grade 3a/b complications were only observed in 11.6% of patients, underlining both well-defined selection criteria and surgical experience.…”

Section: Discussionsupporting

confidence: 85%

Pelvic exenteration surgery in patients with locally advanced castration‐naïve and castration‐resistant, symptomatic prostate cancer

et al. 2020

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Objectives To evaluate retrospectively the surgical, symptomatic and oncological outcomes of pelvic exenteration surgery (PES) in men with significant intrapelvic complications of locally advanced castration‐sensitive (CSPC) and castration‐resistant prostate cancer (CRPC). Patients and Methods A total of 103 patients with locally advanced progressive and symptomatic CSPC or CRPC underwent PES (radical cystoprostatectomy, n = 71 [68.9%]; radical prostatectomy with continent vesicostomy, n = 9 [8.7%]; total exenteration, n = 23 [22.3%]). All patients underwent local staging via magnetic resonance imaging, cystoscopy and rectoscopy. Systemic staging was carried out with chest, abdominal and pelvic computed tomography scans and bone scans. Peri‐operative complications were assessed according to Clavien–Dindo classification. Symptom‐free and overall survival were evaluated using the Kaplan–Meier method. Statistical tests were two‐tailed with a P value <0.05 taken to indicate statistical significance. Results After a median (range) follow‐up of 36.5 (3–123) months, the symptom‐free survival rate at 1 and 3 years was 89.2% (n = 89) and 64.1% (n = 66), respectively. The median symptom‐free survival was 27.9 months. A total of 78.6% of the patients were symptom‐free during their remaining lifetime. The overall survival rate at 1 and 3 years was 92.2% and 43.7%, respectively, and the median overall survival was 33.6 months. Clavien–Dindo grades 2, 3 and 4 complications developed in 31 (30.6%), 12 (11.6%) and eight patients (8.1%), respectively. Conclusion Pelvic exenteration surgery is technically feasible in well‐selected patients, resulting in symptom relief in >90% of patients, covering 80% of their remaining lifetime.

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Section: Discussionsupporting

confidence: 85%

Pelvic exenteration surgery in patients with locally advanced castration‐naïve and castration‐resistant, symptomatic prostate cancer

et al. 2020

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“…In detail, eight studies reported smoking status as a dichotomous variable considering current and former smokers versus never smokers [24][25][26][27][28][29][30][31], two studies distinguished patients between current smokers and former and never smokers [32,33], while 11 studies categorized patients as current smokers and former smokers within 1 yr from the date of surgery versus former smokers for >1 yr and never smokers [14,[34][35][36][37][38][39][40][41][42][43]. Only one study by Schmid et al [44] reported smoking status considering current smokers separately from nonsmokers and ex-smokers.…”

Section: Study Populationmentioning

confidence: 99%

“…In these studies, complication rates ranged from 31.7% to 80.5%. This high variability between studies depends mostly on discrepancy in reporting complications (ie, urinary or bowel-anastomotic complications only; overall, medical, and surgical complications), timing of recorded onset of complications (ie, 30 or 90 postoperative days after surgery), urinary diversion (UD) type, and adopted surgical approach (open vs laparoscopic vs robotic) [13,[35][36][37]39,41,[44][45][46][47][48].…”

Section: Overall Postoperative Complicationsmentioning

confidence: 99%

Section: Hospital Readmission After Rcmentioning

confidence: 99%

“…Two studies explored the impact of smoking status on hospital readmission after RC [35,49]. Mannas et al [35] extracted perioperative data of 223 patients treated with RC at one institution. Thirty-day readmission was registered in 30 (13.5%) patients, and the authors were not able to identify significant clinical and surgical predictors of readmission at uni-and multivariable analyses.…”

Section: Hospital Readmission After Rcmentioning

confidence: 99%

See 2 more Smart Citations

Impact of Smoking Habit on Perioperative Morbidity in Patients Treated with Radical Cystectomy for Urothelial Bladder Cancer: A Systematic Review and Meta-analysis

Tellini

Mari

Muto

et al. 2021

European Urology Oncology

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Radikale pelvine Tumorchirurgie bei Patienten mit einem lokal fortgeschrittenen, symptomatischen kastrationsresistenten Prostatakarzinom

Kanzelmeyer

Bludau

Pfister

et al. 2021

Urologe

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Zusammenfassung Ziel der Arbeit Die retrospektive Evaluation der klinischen Ergebnisse nach palliativer pelviner Tumorchirurgie (ppTC) bei subvesikalen und supravesikalen Komplikationen eines lokal symptomatisch fortgeschrittenen kastrationsresistenten (CRPC) Prostatakarzinoms. Patienten und Methoden Insgesamt 84 Patienten mit lokal fortgeschrittenem und symptomatischem CRPC erhielten eine radikale Zystoprostatektomie (n = 71, 83,3 %) oder anteriore und posteriore Exenteration (n = 13, 16,7 %). Das lokale Staging erfolgte mittels MRT des Beckens, Zystoskopie und Rektoskopie. Ein systemisches Staging erfolgte mittels Computertomographie von Thorax, Abdomen, Becken sowie Skelettszintigraphie. Die perioperativen Komplikationen wurden nach Clavien-Dindo-Klassifikation evaluiert. Das primäre Studienziel war das symptomfreie Überleben (sÜL, Fehlen von Symptomen am unteren oder oberen Harntrakt, fehlende endoluminale oder perkutane Intervention). Ergebnisse Nach einem medianen Follow-up von 43,5 (3–139) Monaten betrug das sÜL nach einem und drei Jahren 95,2 % bzw. 86,7 %. Insgesamt 86,7 % der Patienten blieben für ihre gesamte verbleibende Lebensdauer bezüglich lokaler Symptome beschwerdefrei. Das OS nach einem und drei Jahren betrug 92,9 % bzw. 54,7 %. Clavien-Dindo-Grad-2-, -3- und -4-Komplikationen ergaben sich in 19 (22,6 %), 7 (8,3 %) bzw. 3 (3,6 %) Patienten. Schlussfolgerungen Die ppTC ist mit einer geringen Komplikationsrate möglich und führt zu deutlicher Symptomlinderung bei ca. 90 % der Patienten, von denen > 80 % für die verbleibende Lebenszeit beschwerdefrei verbleiben. Voraussetzung sind die Patientenauswahl, ein interdisziplinäres Vorgehen und eine entsprechende chirurgische Expertise.

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Predicting complications following radical cystectomy with the ACS NSQIP universal surgical risk calculator

Cited by 15 publications

References 9 publications

Pelvic exenteration surgery in patients with locally advanced castration‐naïve and castration‐resistant, symptomatic prostate cancer

Pelvic exenteration surgery in patients with locally advanced castration‐naïve and castration‐resistant, symptomatic prostate cancer

Impact of Smoking Habit on Perioperative Morbidity in Patients Treated with Radical Cystectomy for Urothelial Bladder Cancer: A Systematic Review and Meta-analysis

Radikale pelvine Tumorchirurgie bei Patienten mit einem lokal fortgeschrittenen, symptomatischen kastrationsresistenten Prostatakarzinom

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