Preliminary study of Microfabricated Glow Discharge Plasma for Mass Spectrometry Imaging

Plasma‐based ambient mass spectrometry: Recent progress and applications

“…MFGDP involves electron capture, proton abstraction reaction, nucleophilic attack, ion-molecule attachment, decomposition, and anion attachment mechanisms in the negative mode (Tian et al, 2017). Until now, MFGDP has been successfully applied for the detection of explosives (Tian et al, 2017), pharmaceuticals, tobacco, pesticide residues in fruits and vegetables (Wang et al, 2015), and mass spectrometry imaging of handwritings and nutrients distribution in the winter jujube (Tian et al, 2016). The LODs can reach as low as fg/mm 2 , and the RSD values achieve 10% and 20% manually.…”

Exploration and performance evaluation of microwave‐induced plasma with different discharge gases for ambient desorption/ionization mass spectrometry

“…[2,3] Moreover, DESI is also widely applied in mass spectrometry imaging. [4][5][6][7] Since then, many ambient desorption/ionization sources [8][9][10][11] have been reported, including several atmospheric plasma-based techniques, [12][13][14] such as direct analysis in real time (DART), [15][16][17][18] the low-temperature plasma (LTP) probe, [19][20][21] flowing atmospheric pressure afterglow (FAPA), [22][23][24][25] plasma-assisted desorption/ ionization (PADI), [26][27][28] dielectric barrier discharge ionization (DBDI), [29][30][31] microfabricated glow discharge plasma (MFGDP), [32][33][34][35] and microplasma probe desorption/ ionization (MPPDI). [36] These methods are associated with the generation of a direct current or radio-frequency (rf) electrical discharge between a pair of electrodes contacting with a flowing gas such as argon or helium.…”