Preparation and characterization of bioactive mesoporous wollastonite – Polycaprolactone composite scaffold

Wei, Jie; Chen, Fangping; Shin, Jung-Woog; Hong, Hao; Dai, Chenglong; Su, Jiacan; Liu, Changsheng

doi:10.1016/j.biomaterials.2008.10.046

Cited by 142 publications

(97 citation statements)

References 36 publications

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“…There are a number of ways to prepare the scaffolds (Gomes et al, 2006;Petrie Aronin et al 2008;Wei et al, 2009). The solution casting/ particulate leaching method is the most popular one, because of the simple equipment, controllable pore size, and porosity.…”

Section: Discussionmentioning

confidence: 99%

The Use of Zein and Shuanghuangbu for Periodontal Tissue Engineering

Chen

et al. 2010

Int J Oral Sci

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Aim Tissue engineering is a promising area with a broad range of applications in the fields of regenerative medicine and human health. The emergence of periodontal tissue engineering for clinical treatment of periodontal disease has opened a new therapeutic avenue. The choice of scaffold is crucial. This study was conducted to prepare zein scaffold and explore the suitability of zein and Shuanghuangbu for periodontal tissue engineering. Methodology A zein scaffold was made using the solvent casting/particulate leaching method with sodium chloride (NaCl) particles as the porogen. The physical properties of the zein scaffold were evaluated by observing its shape and determining its pore structure and porosity. Cytotoxicity PDLCs. Altogether, these findings provide the basis for in vivo testing on animals.

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Section: Discussionmentioning

confidence: 99%

The Use of Zein and Shuanghuangbu for Periodontal Tissue Engineering

Chen

et al. 2010

Int J Oral Sci

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“…Elucidating the powerful effects that drug combinations provide when applied synergistically, represents a powerful treatment platform. (114)(115)(116)(117) Although the administration of single agents has been shown to support angiogenesis in animal models, there are still problems associated with vessel stability and maturity. (118,119) The complex process of cell migration, differentiation and proliferation requires specific growth factors, which are both time-dependent and spatially distributed.…”

Section: The Case For Combining Biological Therapiesmentioning

confidence: 99%

Biomaterial‐Enhanced Cell and Drug Delivery: Lessons Learned in the Cardiac Field and Future Perspectives

et al. 2016

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Heart failure is a significant clinical issue. It is the cause of enormous healthcare costs worldwide and results in significant morbidity and mortality. Cardiac regenerative therapy has progressed considerably from clinical and preclinical studies delivering simple suspensions of cells, macromolecule, and small molecules to more advanced delivery methods utilizing biomaterial scaffolds as depots for localized targeted delivery to the damaged and ischemic myocardium. Here, regenerative strategies for cardiac tissue engineering with a focus on advanced delivery strategies and the use of multimodal therapeutic strategies are reviewed.

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“…m-BG was synthesized by using nonionic block copolymer EO 20 PO 70 EO 20 (Pluronic P123, Boston, USA) (Sigmaaldrich, Shanghai Trading Co., Ltd, Shanghai, China) as the template agent, 4 and tetraethyl orthosilicate (Sinopharm Chemical Reagent Co., Ltd, Shanghai, China) as the silica source. P123 (8 g) was dissolved in 120 mL ethanol under stirring for 2 hours, and 13.4 g of tetraethyl orthosilicate and 4 g of 1M hydrochloride (Sinopharm Chemical Reagent Co., Ltd, Shanghai, China) were added to the mixed solution of P123 and ethanol.…”

Section: Preparation Of M-bgmentioning

confidence: 99%

Composite scaffolds of mesoporous bioactive glass and polyamide for bone repair

Cao²,

Yu³

et al. 2012

IJN

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A bone-implanted porous scaffold of mesoporous bioglass/polyamide composite (m-BPC) was fabricated, and its biological properties were investigated. The results indicate that the m-BPC scaffold contained open and interconnected macropores ranging 400-500 µm, and exhibited a porosity of 76%. The attachment ratio of MG-63 cells on m-BPC was higher than polyamide scaffolds at 4 hours, and the cells with normal phenotype extended well when cultured with m-BPC and polyamide scaffolds. When the m-BPC scaffolds were implanted into bone defects of rabbit thighbone, histological evaluation confirmed that the m-BPC scaffolds exhibited excellent biocompatibility and osteoconductivity, and more effective osteogenesis than the polyamide scaffolds in vivo. The results indicate that the m-BPC scaffolds improved the efficiency of new bone regeneration and, thus, have clinical potential for bone repair.

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Preparation and characterization of bioactive mesoporous wollastonite – Polycaprolactone composite scaffold

Cited by 142 publications

References 36 publications

The Use of Zein and Shuanghuangbu for Periodontal Tissue Engineering

The Use of Zein and Shuanghuangbu for Periodontal Tissue Engineering

Biomaterial‐Enhanced Cell and Drug Delivery: Lessons Learned in the Cardiac Field and Future Perspectives

Composite scaffolds of mesoporous bioactive glass and polyamide for bone repair

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