Prevalence and age-wise distribution of Human Papillomavirus type 16/18 infections among hospital screened women of a peri-urban area in West Bengal: Impact of socio-demographic factors

Bhattacharya, Amrapali; Sen, Shrinka; Mandal, Paramita; Saha, Sweta Sharma; Sarkar, Somosree; Pathak, Om Prakash; Biswas, Lena; Roy, Jayeeta; Banerjee, Rimpa; Chowdhury, Ranita Roy; Pal, Manidip; Mukherjee, Ankur; Sengupta, Shamik

doi:10.1016/j.canep.2018.03.005

Cited by 9 publications

(12 citation statements)

References 53 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The predominance of HPV16 among the general population is also evident based on data available from some regions of India [ 9 , 11 ] including an earlier study from our group [12] . A recent study from our group has also shown the preponderance of HPV16 infection among women seeking healthcare at a hospital outpatient department [13] .…”

Section: Introductionmentioning

confidence: 70%

Predominance of genomically defined A lineage of HPV16 over D lineage in Indian patients from eastern India with squamous cell carcinoma of the cervix in association with distinct oncogenic phenotypes

Mandal

Bhattacharjee

Sen

et al. 2022

Translational Oncology

Self Cite

View full text Add to dashboard Cite

Section: Introductionmentioning

confidence: 70%

Predominance of genomically defined A lineage of HPV16 over D lineage in Indian patients from eastern India with squamous cell carcinoma of the cervix in association with distinct oncogenic phenotypes

Mandal

Bhattacharjee

Sen

et al. 2022

Translational Oncology

Self Cite

View full text Add to dashboard Cite

“…In addition to following the standard and validated assays for HPV screening, various laboratories also use in-house PCR-based [ 184 , 185 ] and commercial kits for HPV screening. An Indian team adopted a fluorescence-based PCR assay developed by Schmitt and colleagues in IACR (Lyon, France).…”

Section: Hpv Screeningmentioning

confidence: 99%

Current Updates on Cancer-Causing Types of Human Papillomaviruses (HPVs) in East, Southeast, and South Asia

Xia

Long

et al. 2021

Cancers

View full text Add to dashboard Cite

Human papillomavirus (HPV) infection remains one of the most prominent cancer-causing DNA viruses, contributing to approximately 5% of human cancers. While association between HPV and cervical cancers has been well-established, evidence on the attribution of head and neck cancers (HNC) to HPV have been increasing in recent years. Among the cancer-causing HPV genotypes, HPV16 and 18 remain the major contributors to cancers across the globe. Nonetheless, the distribution of HPV genotypes in ethnically, geographically, and socio-economically diverse East, Southeast, and South Asia may differ from other parts of the world. In this review, we garner and provide updated insight into various aspects of HPV reported in recent years (2015–2021) in these regions. We included: (i) the HPV genotypes detected in normal cancers of the uterine cervix and head and neck, as well as the distribution of the HPV genotypes by geography and age groups; (ii) the laboratory diagnostic methods and treatment regimens used within these regions; and (iii) the oncogenic properties of HPV prototypes and their variants contributing to carcinogenesis. More importantly, we also unveil the similarities and discrepancies between these aspects, the areas lacking study, and the challenges faced in HPV studies.

show abstract

“…Other important cofactors like host genetic variations, weak immune system, and lifestyles also make a woman more susceptible to HPV infection 16 . In West Bengal, many previous studies were conducted to evaluate the HPV prevalence among women in rural and peri‐urban areas 17–19 . But there are very limited reports about the HPV prevalence among tribal women in India.…”

Section: Introductionmentioning

confidence: 99%

“…16 In West Bengal, many previous studies were conducted to evaluate the HPV prevalence among women in rural and peri-urban areas. [17][18][19] But there are very limited reports about the HPV prevalence among tribal women in India. A study on tribal women from Madhya Pradesh, Jharkhand, and Chhattisgarh reported that HPV prevalence was high in tribal women.…”

mentioning

confidence: 99%

The influence of IL1RN VNTR polymorphism on HPV infection among some tribal communities

Goswami

Bhuniya²,

Chatterjee

et al. 2021

Journal of Medical Virology

Self Cite

View full text Add to dashboard Cite

Persistent infection of human Papillomavirus is the main etiological factor for cervical cancer. Austro-Asiatic tribes are early settlers in India and they have unique genetic variations compared to other people. The immunological response is crucial for the prevention of viral associated diseases. Interleukin-1 receptor antagonist (IL-1RN) is considered being an important regulator of host immune surveillance.A total of 45 Santali tribal women and 10 Kora tribal women were enrolled in the present study and demographic variables were recorded during collection. Genomic DNA was extracted from cervical/vaginal swab samples. IL1RN variable number of tandem repeats (VNTR) polymorphisms and HPV types were determined by PCR-based assay. Association between IL1RN VNTR polymorphisms with the HPV infections among the tribal communities was determined by logistic regression analysis.HPV18 prevalence was significantly higher among tribal women. We observed that the polymorphism A2*A2 (p = 0.022; odds ratio [OR] (95% confidence interval [CI]) = 0.16 (0.03-0.86)] were more resistant to oncogenic HPV infection. Use of oral contraceptives was associated with higher relative risk (p = 0.008; OR [95% CI] = 5.39 [1.47-19.8]) for oncogenic HPV18 positivity among the tribal women. The A2 allele homozygosity of IL1RN VNTR was identified to be associated with the protection from oncogenic HPV infection among various tribal communities of West Bengal and therefore may be a useful marker of host immune response among them.

show abstract

Prevalence and age-wise distribution of Human Papillomavirus type 16/18 infections among hospital screened women of a peri-urban area in West Bengal: Impact of socio-demographic factors

Cited by 9 publications

References 53 publications

Predominance of genomically defined A lineage of HPV16 over D lineage in Indian patients from eastern India with squamous cell carcinoma of the cervix in association with distinct oncogenic phenotypes

Predominance of genomically defined A lineage of HPV16 over D lineage in Indian patients from eastern India with squamous cell carcinoma of the cervix in association with distinct oncogenic phenotypes

Current Updates on Cancer-Causing Types of Human Papillomaviruses (HPVs) in East, Southeast, and South Asia

The influence of IL1RN VNTR polymorphism on HPV infection among some tribal communities

Contact Info

Product

Resources

About