Prevalence and Antimicrobial Susceptibility Pattern of Urinary Tract Infection among Pregnant Women Attending Hargeisa Group Hospital, Hargeisa, Somaliland

Abstract

The aim of this study was to determine the prevalence, antimicrobial susceptibility pattern and associated factors of urinary tract infection (UTI) among pregnant women attending Hargeisa Group Hospital (HGH), Hargeisa, Somaliland. A cross-sectional study was conducted at HGH, Hargeisa, Somaliland and participants were selected by systematic random sampling technique. Clean catch midstream urine samples were collected from 422 participants and cultured and antimicrobial susceptibility pattern was determined for the isolates. Univariable and multivariable logistic regression analyses were utilized to identify the independent risk factors for UTI The prevalence of UTI was 16.4 % (95% CI: 13.3–19.9). The predominant bacteria isolate was E. coli (43.5%). Gram negative bacteria were resistant to ampicillin (96%) and tetracycline (71.4%) and Gram-positive bacteria were also resistant to ampicillin (90%), tetracycline (55%). Multidrug resistance was observed in 89.9% of bacterial isolated. No formal education participants were 3.18 times, previous history of catheterization had 3.22 times and previous history of UTI had 3.73 times more likely to develop UTI than their counterparts respectively. Culture and susceptibility test is vital for appropriate management of UTI in the study area.

Bacterial profile and antibiotic susceptibility pattern of uropathogens causing urinary tract infection in the eastern part of Northern India

“…The most common gram-negative bacteria isolated from samples in our investigation was E. coli (55.0%). These findings are consistent with those of several other published studies where the prevalence of E. coli was 97.0, 92.6, 74.0, 55.0, 49.3, 43.5, 41.9, and 40.0% (Arora et al, 2016;Odoki et al, 2019;Chen et al, 2020;Daoud et al, 2020;Ali et al, 2022;Huang et al, 2022;Jagadeesan et al, 2022;Komagamine et al, 2022). In our study, 10.3389/fmicb.2022.965053…”

“…In our study, 96.0% of the pathogens were MDR, compared to 91.3% in Nepal, 85.5% in Somaliland, 83.0% in Haryana, 45.1% in Tunisia, and 42.6% in China (Ben Ayed et al, 2019;Huang et al, 2022;Malik et al, 2021;Shilpakar et al, 2021;Ali et al, 2022). The inappropriate and indiscriminate use of broad-spectrum antibiotics and prolonged hospital stay are key etiological factors associated with MDR infections (Prestinaci et al, 2015).…”

Molecular study for antibiotic-resistance patterns of extended-spectrum B- Lactamase producing Klebsiella Pneumoniae from a UTI of pregnant women in Diwaniyah (Shamiya city) - Iraq

“…The results of this study demonstrated antibiotic resistance to ceftriaxone (73.68%). These results are similar to those posted earlier by Ali et al 2022. On the other hand, the results disagree with those results previously published by Johnson et al, 2021.…”

Risk factors and practices associated with occurrence of Urinary Tract Infections in Sub-Saharan Africa; A scoping review

“…Twenty studies [19], [20], [34], [43], [21], [22], [24], [25], [27]- [29], [33][30] [31][15], [16], [32], [36], [37], [42] reported the mean age of their study subjects. The lowest mean age was 6 years reported by Fenta et al [27] while the highest mean age was 39 years reported in the study by Nigusse et al [37].…”

“…Twelve studies [21][24] [27][28] [29][18], [33], [34][37] [32], [41][15] investigated residence as a factor for urinary tract infections. None of the above studies found signi cant association between residence and occurrence of UTIs.…”