“…In general, it has been observed that PTH (1-34) exerts a positive effect, favoring bone formation, despite the presence of bone catabolic factors. However, there is lack of evidence evaluating PTH (1-34) in the presence of tobacco, one of the factors most investigated, in clinical studies, with relation to poor bone healing, osteopenia (Popat et al 2009), and osteoporosis (Ward & Klesges 2001;Rozental et al 2010). Thus, this study aimed to investigate the influence of subcutaneous administration of PTH (1-34) on bone around titanium implants inserted in rats submitted to CSI.…”