Prevalence rate of metabolic syndrome and dyslipidemia in a large professional population in Beijing

Li, Zhiyan; Xu, Guobing; Xia, Tian

doi:10.1016/j.atherosclerosis.2005.03.033

Cited by 48 publications

(36 citation statements)

References 10 publications

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“…Thus, controlling BMI appears to have the most potential in reducing the occurrence of the MetS in women with PCOS. Age is regarded as an important risk factor for MetS in both general populations and PCOS patients (36)(37)(38)(39). In our study, the increasing trend was also found in the prevalence of MetS in two different ways for agegrouping that was consistent with previous reports concerning the relationship between age and MetS in PCOS patients (11,13).…”

Section: Discussionsupporting

confidence: 92%

Low prevalence of the metabolic syndrome but high occurrence of various metabolic disorders in Chinese women with polycystic ovary syndrome

Ni¹,

Mo²,

Chen³

et al. 2009

European Journal of Endocrinology

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Objective: Variations in the prevalence of metabolic syndrome (MetS) among women with polycystic ovary syndrome (PCOS) in different races were reported. We sought to report this prevalence and its components in Chinese women with PCOS and compared these characteristics with healthy controls. Design: Anthropometric measurements and biochemical parameters were evaluated in 578 PCOS patients diagnosed by the Rotterdam criteria and 281 age-and body mass index (BMI)-matched controls. International Diabetes Federation criteria for MetS were used. Results: The prevalence of MetS was 16.8% in this study, and 60.7% of patients displayed at least one component of MetS. Among the patients, the rates of dyslipidemia, impaired fasting glucose, and elevated blood pressure were 41.6, 19.8, and 16.1% respectively; the rates of these corresponding components in age-and BMI-matched controls were 14.6, 5.3, and 5.7% respectively. In PCOS patients, the prevalence of MetS was 0.0, 3.9, 20.2, and 51.1% for four different BMI groups respectively; the prevalence of MetS was 7.3, 14.9, 24.2, and 42.4% in the four age groups respectively. Nearly 90% of patients diagnosed with MetS belonged to overweight and obese groups. BMI and age rather than free testosterone, free androgen index, fasting insulin, or sex hormone-binding globulin were included in formulation for predicting MetS according to multivariable logistic regression. Conclusions: Low prevalence of MetS but high occurrence of various metabolic disorders was found in women with PCOS compared with age-and BMI-matched controls in this study. BMI and age appeared to contribute more to developing MetS than other parameters associated with insulin resistance or hyperandrogenism.

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Section: Discussionsupporting

confidence: 92%

Low prevalence of the metabolic syndrome but high occurrence of various metabolic disorders in Chinese women with polycystic ovary syndrome

Ni¹,

Mo²,

Chen³

et al. 2009

European Journal of Endocrinology

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“…The prevalence of metabolic syndrome based on two samples studied in Beijing was shown in Table 4. 30,31 Data that suggest a linkage between the increase in obesity and CVD risks in Beijing residents were presented in Table 6, which were consistent with those based on nationwide data.…”

Section: -2001supporting

confidence: 77%

“…Based on nationally representative data, we found that the prevalence of obesity and obesity-related chronic disease has increased at an alarming rate. Currently the prevalence of overweight, hypertension, dyslipidaemia, metabolic syndrome, and diabetes among Chinese adults is approximately 30,20,20,15, and 3%, respectively. The results from Beijing indicate that economically more developed areas such as large cities in China are facing a more serious situation.…”

Section: Discussionmentioning

confidence: 99%

Is China facing an obesity epidemic and the consequences? The trends in obesity and chronic disease in China

et al. 2006

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Background: Over the past two decades, China has enjoyed impressive economic development, and her citizens have experienced many remarked changes in their lifestyle. These changes are often associated with an increase in obesity and chronic disease. Methods: In this meta-analysis, based on nationally representative data, we studied the current prevalence of obesity and the trends in obesity, mortality and morbidity in China. Results: Between 1992 and 2002, the prevalence of overweight and obesity increased in all gender and age groups and in all geographic areas. Using the World Health Organization body mass index cut points, the combined prevalence of overweight and obesity increased from 14.6 to 21.8%. The Chinese obesity standard shows an increase from 20.0 to 29.9%. The annual increase rate was highest in men aged 18-44 years and women aged 45-59 years (approximately 1.6 and 1.0% points, respectively). In general, male subjects, urban residents, and high-income groups had a greater increase. With the increase in overweight and obesity, obesity-, and diet-related chronic diseases (e.g., hypertension, cardiovascular disease (CVD), and type 2 diabetes) also increased over the past decade and became a more important preventable cause of death. Hypertension increased from 14.4% in 1991 to 18.8% in 2002 in adults; in older adults aged 35-74 years, it increased from 19.7 to 28.6%. Between 1993 and 2003, the prevalence of CVD increased from 31.4 to 50.0%; diabetes increased from 1.9 to 5.6%. During 1990-2003, although total mortality rate (per 100 000) decreased, overall the mortality rate and contribution (as percentages) to total death of obesity-related chronic disease increased, in particular, in rural areas. Mortality rate (per 100 000) of CVD increased from 128 to 145 and its contribution to total death, 27 to 32%, in rural areas; the figures decreased slightly in urban areas. The mortality rate of 'nutrition, endocrinology and metabolism-related disease' (NEMD) increased in both rural and urban areas between 1990 and 2000, 8.0 to 10.6 and 4.9 to 5.3, respectively. The current prevalence of hypertension, dyslipidaemia, metabolic syndrome, and diabetes among Chinese adults is approximately 20, 20, 15, and 3%, respectively. Conclusion: The prevalence of overweight and obesity and obesity-related chronic diseases have increased in China in the past decade. Our findings provide useful information for the projection of future trends and the formulation of national strategies and programmes that can address the challenges of the growing obesity and chronic disease epidemic.

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“…Although the precise mechanism of links between periodontitis and atherosclerosis or preterm labour remains unclear, accumulated data suggest that the serum interleukin (IL)-1β and IL-6 caused by periodontitis may be two of the most important pathways that link periodontitis to the diseases mentioned above [4,[16][17][18][19][20][21][22][23]. Recent data also suggest that a relationship between the serum concentrations of IL-1β and IL-6 and severe periodontitis exist [21,[24][25][26][27][28][29][30].…”

Section: Introductionmentioning

confidence: 99%

Expressions of Interleukin-1β and Interleukin-6 Within Aortas and Uteri of Rats with Various Severities of Ligature-Induced Periodontitis

Guo

You

et al. 2010

Inflammation

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To investigate the associations of periodontitis with histological lesions in some other organs, various severities of periodontitis were induced in rats by 3/0 silk ligatures tied around different numbers of their molar necks. Six weeks after the initial placement of ligatures, all rats were sacrificed by an anaesthetic overdose. The distances from the cemento-enamel junction to the alveolar bone crest within the placement zone of the ligature and their contralateral zone in groups L(2) and L(3) were measured. The levels of interleukin (IL)-1β and IL-6 in serum were assayed by enzyme-linked immunosorbent assay techniques, and those within aortas and uteri were measured by real-time polymerase chain reaction and by immunohistochemistry. We divided the ligature-induced periodontitis models into mild, moderate and severe rat periodontitis and observed that although no association between periodontitis and the serum concentrations of IL-1β was detected, the differences in the severity of rat periodontitis led to varying degrees of elevated expressions of IL-1β and IL-6 within aortas and uteri.

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Prevalence rate of metabolic syndrome and dyslipidemia in a large professional population in Beijing

Cited by 48 publications

References 10 publications

Low prevalence of the metabolic syndrome but high occurrence of various metabolic disorders in Chinese women with polycystic ovary syndrome

Low prevalence of the metabolic syndrome but high occurrence of various metabolic disorders in Chinese women with polycystic ovary syndrome

Is China facing an obesity epidemic and the consequences? The trends in obesity and chronic disease in China

Expressions of Interleukin-1β and Interleukin-6 Within Aortas and Uteri of Rats with Various Severities of Ligature-Induced Periodontitis

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