Preventive chemotherapy for HIV-associated tuberculosis in Uganda: an operational assessment at a voluntary counselling and testing centre

Costs of measures to control tuberculosis/HIV in public primary care facilities in Cape Town, South Africa

“…Setting adherence at 62%, as for other studies, the cost per person completing IPT remained higher (US$ 85) than in Uganda (US$ 24) 19 and Zambia (US$ 42). 18 High adher--ence levels (>95%) have been obtained with antiretroviral programmes in South Africa through adherence counselling, support groups, pill boxes, drug iden--tification charts, daily schedules, diaries and treatment literacy educational mate--rials.…”

“…The cost per person completing six months of IPT (US$ 92) with 57% adherence was higher than the cost re--ported in Uganda with 62% adherence (US$ 24) 19 and from a modelling study in Zambia with an assumed 63% adher--ence (US$ 42), 18 due to the higher cost of personnel and lower adherence to IPT in South Africa.…”

“…The data are relevant in the era of antiretroviral treatment (ART) pro--grammes because VCT is necessary to identify HIV-infected persons and ICF, IPT and CPT remain part of the com--prehensive package of HIV care. There are few studies in developing countries on the cost-effectiveness of VCT, 13 rapid HIV testing, 14 IPT [15][16][17][18][19] and CPT. 20 We measured the costs and estimated the cost-effectiveness of the ProTEST package of TB/HIV interventions in Cape Town, South Africa.…”

Isoniazid prophylaxis for tuberculosis prevention among HIV infected police officers in Dar Es Salaam

“…Low acceptability of INH among HIV infected has also been reported from Uganda at all levels of recruitment to INH preventive therapy (15). The low acceptability of INH in this cohort of PO may to some extent be due to fear of stigmatisation by peers or spouses if individuals are known to be HIV infected through regular medical appointments or regular use of medications as prolonged use of drugs is associated with chronic ill health, and this may be linked with HIV.…”

Preventing opportunistic infections among human immunodeficiency virus-infected adults in African countries.

“…However, isoniazid monotherapy given to individuals with undetected active TB might result in acquired resistance to isoniazid. This is of particular concern among HIV-infected people in whom active TB may be prevalent 34 and difficult to diagnose. It is therefore important to identify individuals with active TB and ensure that they receive full antituberculous treatment.…”