Psoriatic Nephropathy—Does an Entity Exist?

Singh, N. P.; Prakash, Anupam; Kubba, Samir; Ganguli, Anirban; Singh, Anil Kumar; Sikdar, Sunandan; Dinda, Amit Kumar; Grover, Chander; Agarwal, S. K.

doi:10.1081/jdi-42811

Cited by 15 publications

(22 citation statements)

References 12 publications

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“…Its association with psoriasis has been rarely described. Singh et al (2) observed three patients with psoriasis and glomerulonephritis. Psoriasis was accompanied by IgA nephropathy in one of these cases, by focal proliferative glomerulonephritis in the second and by membranous glomerulopathy in the third.…”

Section: Discussionmentioning

confidence: 99%

A Case Report of A Patient of Iga Nephropathy Associated With Psoriasis: A Contribution To The Entity of ‘Psoriatic Nephropathy’

Manchanda¹

2017

IOSR JDMS

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Section: Discussionmentioning

confidence: 99%

A Case Report of A Patient of Iga Nephropathy Associated With Psoriasis: A Contribution To The Entity of ‘Psoriatic Nephropathy’

Manchanda¹

2017

IOSR JDMS

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“…Increased serum levels of IgG, IgA, and IgM immune complexes have been found, and a defect in suppressor T cell function has been defined. [7,8] Elevations in inflammatory markers such as CRP have also been associated with renal involvement. [10,17] However, these studies have not been confirmed through further investigations.…”

Section: H Akoglu Et Almentioning

confidence: 99%

“…[15,16] On the other hand, recent reports have suggested that glomerular disease may be a common accompaniment of psoriasis. [6,7,15] This concept is named psoriatic nephropathy, though a consensus has not been established yet. The main reason of disagreement at this point is the lack of data on pathogenetic mechanisms to demonstrate the exact association between psoriasis and glomerular diseases.…”

Section: H Akoglu Et Almentioning

confidence: 99%

“…[4] Although renal involvement is rare during the course of psoriasis, certain glomerular diseases including secondary renal amyloidosis, Ig A nephropathy, and membranous glomerulopathy were proposed to be more common in psoriatic patients. [5][6][7] In this paper, we describe a patient with psoriasis who developed membranoproliferative glomerulonephritis (MPGN). This is the first reported case that demonstrates the coexistence of MPGN and psoriasis.…”

Section: Introductionmentioning

confidence: 99%

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Membranoproliferative Glomerulonephritis Associated with Psoriasis Vulgaris

et al. 2009

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Psoriasis is a hereditary, chronic inflammatory disorder of the skin. Generally, the psoriatic process is limited to the skin; however, internal organs such as the kidneys may be involved in the course. Several glomerular diseases have been distinguished due to renal histological findings of psoriatic patients to date. The underlying pathogenetic mechanisms of these associations remain unclear because of the limited number of cases. We report a case of primary membranoproliferative glomerulonephritis (MPGN) in a psoriatic patient. This is the first reported case that demonstrates the coexistence of MPGN and psoriasis.

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“…The presence of microalbuminuria (albumin excretion 30–299 mg/24 h) as a subclinical marker of glomerular dysfunction has been described in patients with psoriasis vulgaris [3, 4]. Several studies reported cases with chronic glomerulonephritis, which mainly included IgA and membranous nephropathies [5,6,7,8,9,10]. However, the number of psoriatic patients reported with glomerulonephritis is limited and more data are necessary to clarify the association between psoriasis vulgaris and glomerular disease.…”

Section: Introductionmentioning

confidence: 99%

Mesangial Proliferative Glomerulonephritis with or without IgA Deposits: The Morphological Characters in Psoriasis Vulgaris

Jiao

Xu²,

Li³

et al. 2008

Nephron Clin Pract

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Background/Aim: Chronic glomerulonephritides associated with psoriasis vulgaris have been reported in the literature. However, because of the limited number of cases and the lack of specific histological findings, the existence of psoriatic nephropathy remains controversial. This study was performed to investigate the clinical and morphological characteristics of renal involvement in psoriasis vulgaris. Methods: We studied retrospectively 11 patients with psoriasis vulgaris. All patients had nephritic urinary sediments and underwent percutaneous renal biopsy between January 1997 and December 2006. To fulfill the criteria for the study, none of them had any other discernible chronic disease as a second cause of nephropathy, except for long-standing psoriasis vulgaris. Results: Of the 11 patients, 2 (18%) had impaired renal function and 9 (82%) presented with hematuria. Proteinuria was noted in all patients. Their mean peak ESR was 28.3 ± 29.1 mm/1st h. Renal biopsy specimens revealed common histological features of slight-to-moderate mesangial proliferative glomerulonephritis, with (73%) or without IgA depositions in the mesangial area. Inflammation and vascular lesions were unremarkable in the biopsy specimens. Conclusion: The results from this study demonstrate that mesangial proliferative glomerulonephritis with or without IgA deposits might be the major morphological pattern associated with psoriasis vulgaris.

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Psoriatic Nephropathy—Does an Entity Exist?

Cited by 15 publications

References 12 publications

A Case Report of A Patient of Iga Nephropathy Associated With Psoriasis: A Contribution To The Entity of ‘Psoriatic Nephropathy’

A Case Report of A Patient of Iga Nephropathy Associated With Psoriasis: A Contribution To The Entity of ‘Psoriatic Nephropathy’

Membranoproliferative Glomerulonephritis Associated with Psoriasis Vulgaris

Mesangial Proliferative Glomerulonephritis with or without IgA Deposits: The Morphological Characters in Psoriasis Vulgaris

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