Retracted research is published work that is withdrawn, removed, or otherwise invalidated from the scientific and scholarly record. This may occur for many different reasons, which can include error, misconduct, or fraud. Retracting research is intended to stop its continued citation and use, but many retracted papers continue to be used.Retracted research that is integrated into the scientific publication network via citations—either before or after retraction—enables the inadvertent propagation of potentially unsupported or fabricated data, fundamental errors, and unreproducible results, or can lead to misattribution of results or ideas (e.g., in cases of retraction due to dual publication, plagiarism, or ownership). Research over the past decade has identified a number of factors contributing to the unintentional spread of retracted research. Many retracted papers are not marked as retracted on publisher and aggregator sites, and retracted articles may still be found in readers’ PDF libraries, including in reference management systems such as Zotero, EndNote, and Mendeley. Most publishers do not systematically surveil bibliographies of submitted manuscripts, and most editors do not query whether a citation to a retracted paper is justified. When citing retracted papers, authors frequently do not indicate retraction status in bibliographies or in-text citations.The goal of the Reducing the Inadvertent Spread of Retracted Science: Shaping a Research and Implementation Agenda (RISRS) project is to develop an actionable agenda for reducing the inadvertent spread of retracted science. This includes identifying how the gatekeepers of scientific publications can monitor and disseminate retraction status and determining what other actions are feasible and relevant.The RISRS process included an exploratory environment scan, a scoping review of empirical literature, and successive rounds of stakeholder consultation, culminating in a three-part online workshop (October 26, November 9, and November 16, 2020) that brought together a diverse body of 70 stakeholders to engage in collaborative problem solving and dialogue. Workshop discussions were seeded by materials derived from stakeholder interviews and short original discussion pieces contributed by stakeholders. The online workshop resulted in a set of recommendations to address the complexities of retracted research throughout the scholarly communications ecosystem. Recommendations were iteratively updated and developed through a series of surveys and drafts as well as at a followup meeting online February 16, 2021.The RISRS team solicited feedback from presentations to NISOPlus, the Society for Scholarly Publishing, and the European Association of Science Editors. Implementation actions have started through a COPE task force on taxonomy and discussions about a proposed National Information Standards Organization (NISO) Work Item. We welcome your feedback via the project website https://infoqualitylab.org/projects/risrs2020/ or by email to jodi@illinois.edu. We encourage you to disseminate these recommendations and to envision how you, in your role, and in collaborative partnerships, can make a difference. For instance, you might help form a professional working group to further develop or refine these recommendations; present about retraction and related issues at professional and academic meetings; take on an implementation or policy project; or outline further research to be conducted. Recommendations1. Develop a systematic cross-industry approach to ensure the public availability of consistent, standardized, interoperable, and timely information about retractions.2. Recommend a taxonomy of retraction categories/classifications and corresponding retraction metadata that can be adopted by all stakeholders.3. Develop best practices for coordinating the retraction process to enable timely, fair, unbiased outcomes.4. Educate stakeholders about publication correction processes including retraction and about pre- and post-publication stewardship of the scholarly record.