Quantification of glycated hemoglobin indicator HbA1c through near-infrared spectroscopy

Pan, Tao; Li, Minmiao; Chen, Jiemei; Hou, Xue

doi:10.1142/s1793545813500600

Cited by 23 publications

(14 citation statements)

References 21 publications

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“…As an illustrative example, NIR absorption spectroscopy, which probes the overtone and combination vibrational transitions of the molecules, has been employed to quantify Hb and absolute HbA1c content simultaneously, thereby allowing indirect measurement of HbA1c in hemosylate samples [25]. This result is consistent with Kamath and co-workers’ findings that underline a strong correlation between the glycated hemoglobin values obtained by the spectroscopic method and those obtained by the standard HPLC method [26].…”

Section: Emergence Of Optical Sensing Approachessupporting

confidence: 72%

Emerging trends in optical sensing of glycemic markers for diabetes monitoring

Pandey

Dingari

Spegazzini

et al. 2015

TrAC Trends in Analytical Chemistry

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In the past decade, considerable attention has been focused on the measurement of glycemic markers, such as glycated hemoglobin and glycated albumin, that provide retrospective indices of average glucose levels in the bloodstream. While these biomarkers have been regularly used to monitor long-term glucose control in established diabetics, they have also gained traction in diabetic screening. Detection of such glycemic markers is challenging, especially in a point-of-care setting, due to the stringent requirements for sensitivity and robustness. A number of non-separation based measurement strategies were recently proposed, including photonic tools that are well suited to reagent-free marker quantitation. Here, we critically review these methods while focusing on vibrational spectroscopic methods, which offer highly specific molecular fingerprinting capability. We examine the underlying principles and the utility of these approaches as reagentless assays capable of multiplexed detection of glycemic markers and also the challenges in their eventual use in the clinic.

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Section: Emergence Of Optical Sensing Approachessupporting

confidence: 72%

Emerging trends in optical sensing of glycemic markers for diabetes monitoring

Pandey

Dingari

Spegazzini

et al. 2015

TrAC Trends in Analytical Chemistry

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“…Given that NIR absorption strength is weak, most sample types can be measured directly without preprocessing and reagents. The NIR spectroscopic analysis is a rapid and reagentless technique that has been proven to be a powerful analytical tool for use in agriculture, [9][10][11][12][13] food, 14,15 environment, 16,17 medicine, 18,19 pharmaceuticals, 20 and so on. However, to the best of our knowledge, a quanti¯cation method for TCP using NIR spectroscopy has not been developed yet.…”

Section: Introductionmentioning

confidence: 99%

AO–MW–PLS method applied to rapid quantification of teicoplanin with near-infrared spectroscopy

Chen

Pan

et al. 2017

J. Innov. Opt. Health Sci.

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Teicoplanin (TCP) is an important lipoglycopeptide antibiotic produced by fermenting Actinoplanes teichomyceticus. The change in TCP concentration is important to measure in the fermentation process. In this study, a reagent-free and rapid quanti¯cation method for TCP in the TCP-Tris-HCl mixture samples was developed using near-infrared (NIR) spectroscopy by focusing our attention on the fermentation process for TCP. The absorbance optimization (AO) partial least squares (PLS) was proposed and integrated with the moving window (MW) PLS, which is called AO-MW-PLS method, to select appropriate wavebands. A model set that includes various wavebands that were equivalent to the optimal AO-MW-PLS waveband was proposed based on statistical considerations. The public region of all equivalent wavebands was just one of the equivalent wavebands. The obtained public regions were 1540-1868 nm for TCP and 1114-1310 nm for Tris. The root-mean-square error and correlation coe±cient for leave-oneout cross validation were 0.046 mg mL À1 and 0.9998 mg mL À1 for TCP, and 0.235 mg mL À1 and 0.9986 mg mL À1 for Tris, respectively. All the models achieved highly accurate prediction e®ects, and the selected wavebands provided valuable references for designing specialized spectrometers. This study provided a valuable reference for further application of the proposed methods to TCP fermentation broth and to other spectroscopic analysis¯elds.

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“…The method of quantitative analysis of the content of glycated hemoglobin in human hemolysate samples using near infrared (NIR) spectroscopy and the subsequent processing of the spectra by the movingwindow-partial-least-squares (MWPLS) method was proposed in [132]. The method allows to find the optimal wavelength ranges for determining the content of glycated and non-glycated hemoglobin.…”

Section: J Of Biomedical Photonics and Eng 4(2)mentioning

confidence: 99%

Optical and structural properties of biological tissues under diabetes mellitus

Tuchina

Tuchin

2018

J-BPE

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Abstract. Diabetes mellitus is a serious social and economic problem of modern society because it is widespread and fraught with numerous complications. Therefore, it is necessary to search for new methods of diabetes mellitus diagnostics and treatment and to improve the existing ones, which, in turn, requires thorough investigation of the disease development mechanisms, as well as elaboration of simple and reliable methods and criteria for detecting the complication precursors. In connection with the solution of these problems, in the paper we present an analytical review of recent publications devoted to the study of the changes of structural and optical properties of biological tissues under the conditions of diabetes mellitus development using in vitro models of glycated tissues, in vivo experimental models of diabetes in laboratory animals, and clinical studies.

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Quantification of glycated hemoglobin indicator HbA1c through near-infrared spectroscopy

Cited by 23 publications

References 21 publications

Emerging trends in optical sensing of glycemic markers for diabetes monitoring

Emerging trends in optical sensing of glycemic markers for diabetes monitoring

AO–MW–PLS method applied to rapid quantification of teicoplanin with near-infrared spectroscopy

Optical and structural properties of biological tissues under diabetes mellitus

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