Rate of hospitalization for gynecologic disorders among reproductive-age women in the United States

Velebil, P; Wingo, Phyllis A.; Xia, Zhisen; Wilcox, Lynne S.; Peterson, Herbert B.

doi:10.1016/0029-7844(95)00252-m

Cited by 156 publications

(81 citation statements)

References 2 publications

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“…An increase with age in the prevalence of fibroids during the reproductive years has been demonstrated by several epidemiologic studies (Marshall et al 1997;Ross et al 1986;Velebil et al 1995;Wilcox et al 1994). Studies that define cases by pathologic diagnosis, thus restricting cases to those having surgery (Ross et al 1986), have shown a rapid increase in fibroid diagnoses among women in their forties.…”

Section: Agementioning

confidence: 98%

Etiology and pathogenesis of uterine leiomyomas: a review.

Flake

Andersen

Dixon

2003

Environ Health Perspect

497

392

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Uterine leiomyomas, or fibroids, represent a major public health problem. It is believed that these tumors develop in the majority of American women and become symptomatic in one-third of these women. They are the most frequent indication for hysterectomy in the United States. Although the initiator or initiators of fibroids are unknown, several predisposing factors have been identified, including age (late reproductive years), African-American ethnicity, nulliparity, and obesity. Nonrandom cytogenetic abnormalities have been found in about 40% of tumors examined. Estrogen and progesterone are recognized as promoters of tumor growth, and the potential role of environmental estrogens has only recently been explored. Growth factors with mitogenic activity, such as transforming growth factor-β 3, basic fibroblast growth factor, epidermal growth factor, and insulin-like growth factor-I, are elevated in fibroids and may be the effectors of estrogen and progesterone promotion. These data offer clues to the etiology and pathogenesis of this common condition, which we have analyzed and summarized in this review.

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Section: Agementioning

confidence: 98%

Etiology and pathogenesis of uterine leiomyomas: a review.

Flake

Andersen

Dixon

2003

Environ Health Perspect

497

392

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“…This is in contrast to a study conducted 20 years ago using National Hospital Discharge Survey data that found rates of hospital discharges for menstrual disorders were greatest among women ages 40-44 years and rates of menstrual disorders for non-white women were higher than rates for White women, though this difference was not statistically significant. 16 However, the earlier study focused on hospitalization for menstrual disorders and should be interpreted cautiously within the context of current medical practices. Hospitalizations for AUB for women not undergoing hysterectomy have decreased dramatically over the past few decades, 15 and although women with AUB may be younger, they may be less likely to need hospitalization for their problem.…”

Section: 4mentioning

confidence: 99%

Abnormal Uterine Bleeding, Health Status, and Usual Source of Medical Care: Analyses Using the Medical Expenditures Panel Survey

Matteson

Raker

Clark

et al. 2013

Journal of Women's Health

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Background: Traditionally, research on abnormal uterine bleeding (AUB) focused on measured menstrual blood loss. However, the main burden of this symptom from the patient perspective is its impact on quality of life. Better describing the demographic characteristics, quality of life, and utilization of medical care of women with AUB could assist with health resource planning for this population. Methods: We analyzed data from the Medical Expenditures Panel Survey from 2002 to 2010. AUB was identified by International Classification of Diseases, ninth edition (ICD-9) code group 626, disorders of menstruation and other abnormal bleeding from the female genital tract. Health-related quality of life was assessed by the Shortform 12 Health Survey (SF-12, QualityMetric) physical and mental component summary scores (PCS and MCS). Poorer health-related quality of life was defined as PCS or MCS < 50. Odds ratios (OR) and 95% confidence intervals (CI) for the association of AUB with poorer SF-12 scores and having a usual source of care were estimated by multivariable logistic regression models. Results: Data analyzed represented an annual average of 56.2 million nonpregnant women between ages 18 and 50 years. We estimate that 1.4 million women per year (95% CI: 1.3-1.5 million) reported AUB. Women with AUB were more likely to be younger, Caucasian, and obese than women without AUB. Compared to women without AUB, women with AUB had greater odds of a poorer PCS score (OR = 1.30, 95% CI: 1.10-1.55), a poorer MCS score (OR = 1.28, 95% CI: 1.10-1.51), and a usual source of care (OR = 1.85, 95% CI: 1.44-2.38). Conclusions: AUB is associated with diminished physical and mental health status and having a usual source of medical care.

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“…Between 1990 and 1998, it was the third most common gynecological diagnosis listed in the hospital discharge summaries of women aged 15 to 44 years. 22 Endometriosis results in lost productivity, hospitalizations, and surgical procedures, as well as outpatient and prescription drug costs. Many women resort to bed rest during bouts of endometriosis-related pain, with almost half the women with endometriosis in one study reporting the need for an average of 17.8 days of bed rest in the previous 12 23 The aims of endometriosis treatment are to eliminate symptoms, reduce the process of inflammation, and limit tissue destruction that might result from long-standing disease.…”

Section: Actuarial Analysis Of Private Payer Administrative Claims Damentioning

confidence: 99%

Actuarial Analysis of Private Payer Administrative Claims Data for Women With Endometriosis

Mirkin¹,

Murphy-Barron²,

Iwasaki³

2007

JMCP

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Authors ConTeMpoRARy SuBJeCTDaviD Mirkin is a principal and Catherine Murphy-Barron and kosuke iwasaki are consulting actuaries, Milliman, inc., new york, new york. author CorresponDenCe: David Mirkin, MD, principal, Milliman, inc., one penn plaza, 38th Fl., new york, ny 10119. tel: (646) Fax: (646) 473-3199; e-mail: david.mirkin@milliman.com. Copyright© 2007, academy of Managed Care pharmacy. all rights reserved.BACKGROUND: Endometriosis is a painful, chronic disease affecting 5.5 million women and girls in the United States and Canada and millions more worldwide. The usual age range of women diagnosed with endometriosis is 20 to 45 years. Endometriosis has an estimated prevalence of 10% among women of reproductive age, although estimates of prevalence vary greatly. Endometriosis is the most common gynecological cause of chronic pelvic pain, but published information on its associated medical care costs is scarce.

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Rate of hospitalization for gynecologic disorders among reproductive-age women in the United States

Cited by 156 publications

References 2 publications

Etiology and pathogenesis of uterine leiomyomas: a review.

Etiology and pathogenesis of uterine leiomyomas: a review.

Abnormal Uterine Bleeding, Health Status, and Usual Source of Medical Care: Analyses Using the Medical Expenditures Panel Survey

Actuarial Analysis of Private Payer Administrative Claims Data for Women With Endometriosis

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