Recyclable biocatalytic composites of lipase-linked magnetic macro-/nano-particles for glycerol carbonate synthesis

Tudorache, Mădălina; Proteşescu, Loredana; Negoi, Alina; Pârvulescu, Vasile I.

doi:10.1016/j.apcata.2012.06.016

Cited by 42 publications

(25 citation statements)

References 29 publications

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“…380,381 The lipase enzyme was covalently attached to magnetic NPs via 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide or glutaraldehyde. 382 The developed magnetic biocatalysts showed about 3-fold higher catalytic efficiency (3.52 Â 10 5 h À1 TOF) than the free lipase (1.16 Â 10 5 h À1 TOF), which was explained as a beneficial effect of the lipase immobilisation and the resulting lipase-Fe 3 O 4 interactions. 382,383 Similar catalytic performances were also achieved when starting from ''crude'' glycerol feed extracted during biodiesel synthesis.…”

Section: Non-core-shell Iron-based Magnetic Catalystsmentioning

confidence: 93%

“…382 The developed magnetic biocatalysts showed about 3-fold higher catalytic efficiency (3.52 Â 10 5 h À1 TOF) than the free lipase (1.16 Â 10 5 h À1 TOF), which was explained as a beneficial effect of the lipase immobilisation and the resulting lipase-Fe 3 O 4 interactions. 382,383 Similar catalytic performances were also achieved when starting from ''crude'' glycerol feed extracted during biodiesel synthesis. 384 The efficiency of these magnetic biocatalysts has also been proven for the transesterification of oils extracted from soybean, sunflower, rape, corn, olive, and palm.…”

Section: Non-core-shell Iron-based Magnetic Catalystsmentioning

confidence: 93%

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Functionalised heterogeneous catalysts for sustainable biomass valorisation

et al. 2018

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Efficient transformation of biomass to value-added chemicals and high-energy density fuels is pivotal for a more sustainable economy and carbon-neutral society. In this framework, developing potential cascade chemical processes using functionalised heterogeneous catalysts is essential because of their versatile roles towards viable biomass valorisation. Advances in materials science and catalysis have provided several innovative strategies for the design of new appealing catalytic materials with well-defined structures and special characteristics. Promising catalytic materials that have paved the way for exciting scientific breakthroughs in biomass upgrading are carbon materials, metal-organic frameworks, solid phase ionic liquids, and magnetic iron oxides. These fascinating catalysts offer unique possibilities to accommodate adequate amounts of acid-base and redox functional species, hence enabling various biomass conversion reactions in a one-pot way. This review therefore aims to provide a comprehensive account of the most significant advances in the development of functionalised heterogeneous catalysts for efficient biomass upgrading. In addition, this review highlights important progress ensued in tailoring the immobilisation of desirable functional groups on particular sites of the above-listed materials, while critically discussing the role of consequent properties on cascade reactions as well as on other vital processes within the bio-refinery. Current challenges and future opportunities towards a rational design of novel functionalised heterogeneous catalysts for sustainable biomass valorisation are also emphasized.

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Section: Non-core-shell Iron-based Magnetic Catalystsmentioning

confidence: 93%

Section: Non-core-shell Iron-based Magnetic Catalystsmentioning

confidence: 93%

Functionalised heterogeneous catalysts for sustainable biomass valorisation

et al. 2018

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“…This characteristic led in higher loading of enzyme, and subsequently biocatalytic activity per unit mass was remarkably increased. For example, Tudorache et al observed that the optimum enzyme loading of functionalized magnetic NPs with the diameter of 50 nm (3.1 μg enzyme/mg support) was up to 20 times more than that of microparticles with the diameter of 500 nm (0.15 μg enzyme/mg support) . Furthermore, nanobiocatalysts showed excellent chemical and mechanical stability during bioconversion processes compared to the conventional immobilized enzyme that is a key factor in process design .…”

Section: Advantages and Disadvantages Of The Nanoimmobilized Lipasesmentioning

confidence: 99%

A review on the important aspects of lipase immobilization on nanomaterials

Shuai

Das

Naghdi

et al. 2017

Biotech and App Biochem

131

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Lipase is one of the most widely used enzymes and plays an important role in biotechnological and industrial processes including food, paper, and oleochemical industries, as well as in pharmaceutical applications. However, its aqueous solubility and instability make its application relatively difficult and expensive. The immobilization technique is often used to improve lipase performance, and the strategy has turned out to be a promising method. Immobilized lipase on nanomaterials (NMs) has shown superiority to the free lipase, such as improved thermal and pH stability, longer stable time, and the capacity of being reused. However, immobilization of lipase on NMs also sometimes causes activity loss and protein loading is relatively lowered under some conditions. The overall performance of immobilized lipase on NMs is influenced by mechanisms of immobilization, type of NMs being used, and physicochemical features of the used NMs (such as particle size, aggregation behavior, NM dimension, and type of coupling/modifying agents being used). Based on the specific features of lipase and NMs, this review discusses the recent developments, some mechanisms, and influence of NMs on lipase immobilization and their activity. Multiple application potential of the immobilized lipases has also been considered.

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“… 55 , 62 , 67 For a solvent-free system, various catalysts have been investigated for the GC synthesis, including N435, cross-linked enzyme aggregate onto magnetic particles (CLEMPA), Aspergillus niger (AN), and lipase-linked magnetic macro-/nanoparticles (lipase-MP 3 ). 16 , 21 , 68 − 70 Compared with reported biocatalysts, CALB@nanoflowers had high catalytic activity and even retained a high catalytic efficiency with a GC yield of 70.31% after recycling seven times ( Figure 9 ). The relatively high GC yield and high recyclability demonstrated that CALB@nanoflowers was an efficient biocatalyst for the transesterification of GL with DMC.…”

Section: Results and Discussionmentioning

confidence: 98%

Enzymatic Synthesis of Glycerol Carbonate Using a Lipase Immobilized on Magnetic Organosilica Nanoflowers as a Catalyst

Du¹,

Gao²,

Kong³

et al. 2018

ACS Omega

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For synthesizing glycerol carbonate (GC) by a reaction between glycerol (GL) and dimethyl carbonate (DMC), a lipase immobilized on magnetic organosilica nanoflowers was prepared and utilized as a biocatalyst. Candida antarctica lipase B (CALB) was chosen as a model enzyme for preparing an immobilized biocatalyst (CALB@nanoflowers). The obtained CALB@nanoflowers was characterized using scanning electron microscopy, transmission electron microscopy, and confocal laser scanning microscopy. Effects of GL/DMC molar ratio, biocatalyst amount, temperature, surfactant and molecular sieve addition, and reaction time on the conversion of GL and the selectivity of CALB@nanoflowers were investigated. The optimal catalytic performance (yield of GC: 88.66% and conversion of GL: 94.24%) was achieved under the condition of 1:20 molar ratio of GL to DMC with 0.2 g of molecular sieves added at 50 °C for 24 h. After recycling seven times, the CALB@nanoflowers maintained over 79% of its initial activity and the yield of GC was 70.31%.

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Recyclable biocatalytic composites of lipase-linked magnetic macro-/nano-particles for glycerol carbonate synthesis

Cited by 42 publications

References 29 publications

Functionalised heterogeneous catalysts for sustainable biomass valorisation

Functionalised heterogeneous catalysts for sustainable biomass valorisation

A review on the important aspects of lipase immobilization on nanomaterials

Enzymatic Synthesis of Glycerol Carbonate Using a Lipase Immobilized on Magnetic Organosilica Nanoflowers as a Catalyst

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