Reduction of latex aeroallergens and latex-specific IgE antibodies in sensitized workers after removal of powdered natural rubber latex gloves in a hospital☆☆☆★★★

Allmers, H.; Brehler, R.; Chen, Zhipping; Raulf‐Heimsoth, Monika; Fels, Hubert; Baur, Xaver

doi:10.1016/s0091-6749(98)70026-0

Cited by 139 publications

(67 citation statements)

References 14 publications

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“…IJOMEH 2014;27(1) 101 intervention measure that has already been demonstrated to be effective over a decade ago [28]. In conclusion, the prevalence of latex sensitization in nurses in governmental hospitals in Thailand in this study was 4.4% (range: 2.2-6.6%), which was 2-3 times higher than previously reported.…”

Section: Latex Allergy In Thai Nurses O R I G I N a L P A P E R Scontrasting

confidence: 43%

Latex sensitization and risk factors in female nurses in Thai governmental hospitals

Supapvanich

Povey

Vocht

2014

International Journal of Occupational Medicine and Environmental Health

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Objectives: Exposure to latex allergens in latex gloves can cause occupational health problems in nurses, yet latex gloves are still widely used in Thai hospitals. Therefore, we conducted a study to determine the prevalence of latex sensitization in nurses and identify risk factors associated with sensitization. Materials and Methods: A questionnaire, providing information on personal characteristics, ill-health, working conditions and symptoms related to latex product use, was administered to 363 female nurses working in two tertiary hospitals in southern Thailand. Latex sensitization was confirmed using a solid phase immunoassay to detect anti-latex IgE antibodies. Total glove protein levels were determined by using a modified Lowry method and latex aeroallergens by a competitive inhibition immunoassay. Results: The overall prevalence of latex sensitization was 4.4%. Respiratory symptoms related to latex glove use were significantly associated with latex sensitization (OR = 5.5, 95% CI: 1.57-19). Total glove protein levels ranged 87.8-250.8 μg protein/dm 2 . The prevalence of latex sensitization was higher (6.6% vs. 2.2%) in the hospital where gloves with higher protein levels (82-438 μg/g vs. 86-170 μg/g) were used. Furthermore, latex sensitization prevalence increased from 3% to 5% with increased average departmental aeroallergen concentrations. Conclusions: Latex sensitization prevalence in Thai nurses was higher than previously reported. Respiratory exposure seems to play an important role, in addition to dermal exposure. If latex gloves cannot be replaced by non-latex alternatives, replacement with gloves with lower protein content should be considered.

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Section: Latex Allergy In Thai Nurses O R I G I N a L P A P E R Scontrasting

confidence: 43%

Latex sensitization and risk factors in female nurses in Thai governmental hospitals

Supapvanich

Povey

Vocht

2014

International Journal of Occupational Medicine and Environmental Health

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“…Latex-specific IgE levels decreased in six of seven healthcare workers who avoided use of powdered latex gloves for 12 months [79]. Twenty latex-sensitized anesthesiologists (12 symptomatic, 8 symptomatic) who avoided use of latex gloves for 10 to 15 months became asymptomatic, and 16 of these doctors had decreased levels of latex-specific IgE [80].…”

Section: Reduction or Prevention Of Latex Sensitizationmentioning

confidence: 97%

Occupational allergies caused by latex

Ahmed

Sobczak

Yunginger³

2003

Immunology and Allergy Clinics of North America

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“…There has been a lot of research into the possible ways of reducing the severity of aeroallergen challenge, since it is this exposure route which is associated with the more severe allergic reactions, with much of this work concentrating on air filter systems and the use of powder-free gloves. [49][50][51] Cornstarch, which is used to coat latex gloves, is thought to bind to NRL allergens, thus producing an aeroallergen. 52,53 The use of powder-free gloves not only reduces the incidence of nonimmunological reactions but can reduce latex allergic reactions due to aeroallergen exposure.…”

Section: Nrl Allergens and Their Use In Diagnosismentioning

confidence: 99%

Cataract surgery for natural rubber latex allergic patients

Cheung

Gillow²

2003

Eye

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The prevalence of reactions against natural rubber latex (NRL) is thought to be increasing in both the general public and healthcare workers. These can vary from mild benign skin reactions to bronchospasm, anaphylactic shock, and death. Difficulties exist for ophthalmic departments wishing to establish protocols in providing 'latex-free environments' for patients undergoing cataract surgery. Currently no legislation exists regarding the labelling of NRL-containing products in the United Kingdom with information on a product's NRL content provided by the manufacturer on a voluntary basis only. It is hoped this review article will act as a basic guide in the management of NRL-sensitive patients undergoing cataract surgery in the United Kingdom.

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Reduction of latex aeroallergens and latex-specific IgE antibodies in sensitized workers after removal of powdered natural rubber latex gloves in a hospital☆☆☆★★★

Cited by 139 publications

References 14 publications

Latex sensitization and risk factors in female nurses in Thai governmental hospitals

Latex sensitization and risk factors in female nurses in Thai governmental hospitals

Occupational allergies caused by latex

Cataract surgery for natural rubber latex allergic patients

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