Salinization of the upper aquifer of the northern Elbe-Weser region almost extends to the surface. Chloride content exceeds 250 mg/l and the groundwater is therefore, according to the German Drinking Water Ordinance, not suitable as drinking water. The chloride content in the aquifer originates from early flooding with seawater which occurred during the Holocene sea level rise. Depth and extent of the salinization were mapped by airborne electromagnetic surveys and validated by groundwater analyses. In the transition zone between the marshlands and geest areas, the fresh-saline groundwater interface falls to a depth of > −175 m NHN. Due to the extensive drainage of the marshlands, seepage of fresh groundwater is impeded. Instead, an upconing of the fresh-saline groundwater interface appears due to an upwardly directed hydraulic gradient. Due to climate change, chloride concentrations will increase along the coastlines. Further inland, a decrease of chloride content in near-surface groundwater will occur.