The sustainable development is a main goal of Calabria Region that has promoted a lot of activities to contrast climate change in line with international, European and national targets. In the field of city logistics, the Region can operate only through moral and financial support; a technical and administrative process has been developed including the definition of planning, programming and implementation processes on a regional scale. The realization of city logistics in the Calabria urban centers was planned starting from the Regional Transport Plan (RTP) in 2016, programmed through the Implementation Program in 2017, implemented by a first Call published in the 2018 and a second Call in 2019. The city logistics process has been supported by a structured public engagement through training activities according to the National Coordination Center for Public Engagement (NCCPE) and the Evaluation Program and United States National Security Exercise (HSEEP), adequately specified. Calabria Region policy is oriented to achieve a process of participation and sharing of choices raising the levels of knowledge on the urban freight transport and the sustainability development of cities. The objective is to create an urban logistics with zero CO2 emissions by 2030 according to sustainability targets set at international, European, national level.