Registration of Health-Related Quality of Life in a Cohort of Patients Undergoing Cholecystectomy

Abstract

Background. Assessment of gallstone surgery's impact on quality of life (QoL) requires a reliable instrument with sufficient responsiveness. The instrument should also enable estimation of each individual's expected condition in an unaffected state. Materials and Methods. The Swedish Register for Gallstone Surgery and ERCP (GallRiks) registers indications, complications, results, and QoL-outcome of gallstone surgery. In 2008, 68 hospitals were registered in GallRiks. Between 2007 and 2008, SF-36 (a short form health survey) was filled in 1-2 weeks pre- and 6–9 months postoperatively at five of the units. Expected scores were determined from an age- and gender-matched Swedish population (AGMSP). Results. Of the 330 patients, 212 responded to SF36 pre- and postoperatively (RR = 64%; 212/330). Standardized response means ranged from 0.20 to 0.93 for the SF-36 subscores. Highest responsiveness was seen for bodily pain. Preoperatively, all subscores were significantly lower than in the AGMSP (all P < .05). Six months postoperatively, there was no significant difference between any of the observed and expected quality of life subscales. Conclusion. SF-36 is a useful instrument for measuring the impact of gallstone surgery on QoL. The postinterventional health status equalled or even exceeded the AGMSP for all subscales.

The Swedish Registry of Gallstone Surgery and Endoscopic Retrograde Cholangiopancreatography (GallRiks)

“…The reports are focused on the difference between the preoperative and postoperative outcomes of the bodily pain subscale and physical composite score. The responsiveness of the SF-36 score in patients undergoing cholecystectomy has been assessed, 11 confirming SF-36 as an appropriate patient-related outcome measure for patients undergoing gallstone surgery.…”

Health-Related Quality-of-Life in a cohort undergoing cholecystectomy

“…The Physical Component Summary (PCS) and Bodily Pain were taken as the main outcome measures. BP was selected as outcome measure as it has been shown to have the highest responsiveness in this patient group [4] . The difference between the preoperative and postoperative ratings were used in univariate and multivariate regression analyses to determine which factors had the greatest impact on treatment outcome.…”

“…Consequently, the main outcome measure of elective cholecystectomy is ideally the patient's symptoms and Health-Related QoL after surgery. The SF-36 instrument is used for pre- and postoperative assessment of QoL in GallRiks [4] . At present QoL outcome is only measured and registered at a limited number of units.…”

Physical Activity Modulating Lipid Metabolism in Gallbladder Diseases

“…Of note, patients with gallstone disease generally report decreased physical function and increased bodily pain [104,105]. Several aspects in HRQoL, such as bodily pain or physical function, can improve postoperatively [106]. However, more studies are needed to better explore HRQoL outcomes in gallbladder patients [107].…”