Risk Factors for Oral Mucosal Diseases (Literature Review)

Yatsenko, Anna; Pervov, Yury; Черток, В. М.; Грицина, О. П.; Mosienko, Elizaveta

doi:10.18481/2077-7566-2022-18-3-71-76

Cited by 4 publications

(1 citation statement)

References 34 publications

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“…У пациентов с билиарнозависимым панкреатитом обострение хронического рецидивирующего афтозного стоматита наблюдается чаще -не менее двух раз в год [6,7]. Возникновение афт в полости рта при сопутствующих заболеваниях желудочнокишечного тракта можно объяснить снижением рН ротовой жидкости, что приводит к возникновению впервые и рецидивам хронических заболеваний полости рта [14].…”

Section: хроническийunclassified

Influence of Somatic Status on the Appearance of Recurrent Aphthosis Stomatitis

Komova,

Borisova,

Zheleznyak

et al. 2023

APPLIED

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Recurrent aphthous stomatitis is a polyetiological inflammatory disease of the oral mucosa, characterized by the appearance of aphthous ulcers. The etiology and pathogenesis of this disease have not been finally revealed. There is an imbalance of immunity observed in patients who are suffering from recurrent aphthous stomatitis caused by the influence of certain trigger factors. The purpose is to summarize the literature data on the relationship of somatic status with the occurrence of recurrent aphthous stomatitis. The review considers the pathogenesis of recurrent aphthous stomatitis, as well as possible trigger factors: genetic predisposition, infections, somatic diseases, allergies, stress, and hypovitaminosis. An obligatory link in the pathogenesis of recurrent aphthous stomatitis is an imbalance of immunity - cellular (the production of pro-inflammatory cytokines increases, and the synthesis of anti-inflammatory heat shock proteins decreases) and humoral (an increase in the number of neutrophils and B-lymphocytes, activation of the complement system). Genetic predisposition, some somatic diseases (Behcet's disease) and viral infections (in particular, COVID-19) lead to an imbalance in the immune system. Provoke the occurrence of recurrent aphthous stomatitis infections, diseases of the gastrointestinal tract, stress and insufficiency of B vitamins and trace elements. The indirect effect of trigger circumstances is due to a decrease in the trophism of the oral mucosa, which leads to a local decrease in the number of factors of cellular and humoral immunity and to hyposalivation and a decrease in the pH of the oral fluid, which provokes the reproduction of opportunistic microflora. Based on the analyzed literature data, it can be concluded that the somatic status influences the development of recurrent aphthous stomatitis. Accordingly, patients suffering from recurrent aphthous stomatitis should be referred to a general doctor for evaluation.

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Section: хроническийunclassified

Influence of Somatic Status on the Appearance of Recurrent Aphthosis Stomatitis

Komova,

Borisova,

Zheleznyak

et al. 2023

APPLIED

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Clinical Case: Surgical Rehabilitation of a Patient After Electronic Cigarette Explosion

Chuykin

Topol'nickiy

Davletshin

et al. 2023

Actual Problems in Dentistry

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We have carried out the rehabilitation of a patient after a traumatic injury to the maxillofacial region resulting from the explosion of an electronic cigarette. The patient was treated in the Department of Maxillofacial Surgery of the Republican Children's Clinical Hospital in Ufa. A 16-year-old boy was delivered by an ambulance to the emergency department of the Republican Children's Clinical Hospital in Ufa 30 minutes after the injury. The child was hospitalized in the department of maxillofacial surgery. At stage I, primary surgical treatment was performed, reposition of the free-lying fragment of the upper jaw in the frontal section and fixation of the mucosa of the alveolar process of the upper jaw in the region of 1.3 and 2.4 teeth with vicryl 2.0. The mucosa was mobilized along the transitional fold of the upper jaw in the anterior region, placed in the region of the defect in the upper jaw, and sutured with a 5-0 Vicryl thread. After 6 months, the patient enters the II stage of surgical treatment. The cortical plates were placed in the area of the defect and fixed with titanium screws. After another 6 months, the child enters the III stage of surgical treatment - the removal of titanium screws, the installation of dental implants. Stage IV. Installation of temporary crowns of teeth. As a result of smoking a vape, a teenager received severe traumatic stress. Stage IV of complex surgical treatment was carried out. There are stages of implant prosthetics, which is quite expensive for the patient, since this treatment is not included in the List of State Guarantees. Undoubtedly, vape smoking is a very cost-effective procedure, and very harmful to health in general.

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Evaluating the Efficacy of Synbiotic Mouthwash in Patients with Dyscirculatory Encephalopathy: Observational Clinical Study

Mitronin,

Maksimova,

Ostanina

et al. 2023

Kuban. nauсh. med. vestnik

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Background. At present, the priority direction of medical science and practice is the prevention of dental diseases, especially in patients with somatic pathology. Patients with dyscirculatory encephalopathy develop a complex of neurological disorders, accompanied by impaired motor functions of hands, lips and chewing muscles, which leads to ineffective cleansing of the oral cavity from food residues and formation of soft and mineralized dental deposits on the dental surface. Therefore, these patients should use additional personal hygiene products.Objective. To evaluate the efficacy of hygienic care in patients with dyscirculatory encephalopathy using mouthwash with synbiotic complex.Methods. An observational clinical study was conducted on the basis of Neurology Unit No. 2 of Research Center of Neurology, Department of Cariology and Endodontics and Department of Biological Chemistry, A.I. Yevdokimov Moscow State Medical and Dental University. The study enrolled 82 patients aged from 45 to 74 years with cerebrovascular disease, dyscirculatory encephalopathy, decompensation (I68.7, according to ICD-10). Patients were divided into two study groups: group 1 (n = 44) — patients who used mouthwash with synbiotic complex; group 2 (n = 38) — patients who did not use mouthwash. The efficacy of mouthwash with synbiotic complex was assessed by using an index score of a simplified Greene Vermillion Oral Hygiene Index (OHI-S), Russell Periodontal Index (PI), Papillary Bleeding Index (PBI), and physicochemical parameters of the oral fluid. Statistical processing of the results was carried out using Stat Plus 7 (Analyst Soft Inc., USA).Results. The comparative analysis proved the efficacy of mouthwash with synbiotic complex. The hygienic status improved to (1.50 ± 0.12) points, the state of periodontal tissues — to (PI = (1.94 ± 1.45) points; PBI = (1.12 ± 0.11) points). The hydrogen index (pH) of the oral fluid decreased to weakly alkaline values — (7.92 ± 0.22) points; the activity of alkaline phosphatase decreased by a factor of 1.4, lactate dehydrogenase — by half, aminotransferases — by a factor of 1.3, and D-dimer — by a factor of 1.2.Conclusion. The obtained results demonstrate the efficacy of mouthwash as an additional means for personal hygiene. Mouthwash with synbiotic complex should be included in the daily oral hygiene care for patients with dyscirculatory encephalopathy.

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Risk Factors for Oral Mucosal Diseases (Literature Review)

Cited by 4 publications

References 34 publications

Influence of Somatic Status on the Appearance of Recurrent Aphthosis Stomatitis

Influence of Somatic Status on the Appearance of Recurrent Aphthosis Stomatitis

Clinical Case: Surgical Rehabilitation of a Patient After Electronic Cigarette Explosion

Evaluating the Efficacy of Synbiotic Mouthwash in Patients with Dyscirculatory Encephalopathy: Observational Clinical Study

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